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Western Blot (WB) (Western Blot (WB) analysis of CHD2 polyclonal antibody)

Rabbit CHD2 Polyclonal Antibody | anti-CHD2 antibody

CHD2 Polyclonal Antibody

Reactivity
Human, Mouse, Rat
Applications
Western Blot
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is >95% (by SDS-PAGE).
Synonyms
CHD2; Polyclonal Antibody; CHD2 Polyclonal Antibody; Chromodomain-helicase-DNA-binding protein 2; CHD-2; ATP-dependent helicase CHD2; anti-CHD2 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Specificity
CHD2 polyclonal antibody detects endogenous levels of CHD2 protein.
Purity/Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is >95% (by SDS-PAGE).
Form/Format
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Sequence Length
501
Applicable Applications for anti-CHD2 antibody
Western Blot (WB)
Application Notes
WB: 1:500-1:1000
Immunogen
Recombinant full length Human CHD2.
Preparation and Storage
Store at 4 degree C short term.
Aliquot and store at -20 degree C long term.
Avoid freeze-thaw cycles.

Western Blot (WB)

(Western Blot (WB) analysis of CHD2 polyclonal antibody)

Western Blot (WB) (Western Blot (WB) analysis of CHD2 polyclonal antibody)
Related Product Information for anti-CHD2 antibody
The CHD family of proteins is characterized by the presence of chromo (chromatin organization modifier) domains and SNF2-related helicase/ATPase domains. CHD proteins alter gene expression by modifying chromatin structure, thereby altering access of the transcriptional machinery to its chromosomal DNA template. Chromodomain helicase DNA binding protein 2, also known as CHD2, is a member of the SNF2/RAD54 helicase family of chromatin remodeling and DNA-binding proteins (CDH proteins). Consisting of 1, 828 amino acids, CHD2 is expressed in the nucleus and contains two chromo domains, a helicase ATP-binding domain and a helicase C-terminal domain. CHD2 is suggested to play a critical role in development, hematopoiesis and tumor suppression. Mutations in the gene encoding CHD2 may be the cause of glomerulopathy, proteinuria and significantly impaired kidney function. CHD2 exists as two alternatively spliced isoforms.

NCBI and Uniprot Product Information

NCBI GI #
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
~ 260kDa
NCBI Official Full Name
chromodomain-helicase-DNA-binding protein 2 isoform 2
UniProt Protein Name
Chromodomain-helicase-DNA-binding protein 2
UniProt Gene Name
CHD2
UniProt Synonym Gene Names
CHD-2
UniProt Entry Name
CHD2_HUMAN

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Product Notes

The CHD2 chd2 (Catalog #AAA3011475) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The CHD2 Polyclonal Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's CHD2 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). WB: 1:500-1:1000. Researchers should empirically determine the suitability of the CHD2 chd2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CHD2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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