Immunohistochemistry (IHC)
(The image on the left is immunohistochemistry of paraffin-embedded Human ovarian cancer tissue using CHAMP1 Antibody at dilution 1/35, on the right is treated with synthetic peptide. (Original magnification: x200))
Rabbit anti-Human CHAMP1 Polyclonal Antibody | anti-CHAMP1 antibody
CHAMP1 Antibody
Immunohistochemistry (IHC)
(The image on the left is immunohistochemistry of paraffin-embedded Human ovarian cancer tissue using CHAMP1 Antibody at dilution 1/35, on the right is treated with synthetic peptide. (Original magnification: x200))
Immunohistochemistry (IHC)
(The image on the left is immunohistochemistry of paraffin-embedded Human ovarian cancer tissue using CHAMP1 Antibody at dilution 1/35, on the right is treated with synthetic peptide. (Original magnification: x200))
Immunohistochemistry (IHC)
(The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using CHAMP1 Antibody at dilution 1/35, on the right is treated with synthetic peptide. (Original magnification: x200))
Immunohistochemistry (IHC)
(The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using CHAMP1 Antibody at dilution 1/35, on the right is treated with synthetic peptide. (Original magnification: x200))
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a zinc finger protein that functions as a regulator of chromosome segregation in mitosis. The encoded protein is required for correct alignment of chromosomes on the metaphase plate, and plays a role in maintaining the attachment of sister kinetochores to microtubules from opposite spindle poles. Mutations in this gene are associated with autosomal dominant mental retardation-40. [provided by RefSeq, Oct 2016]
Uniprot Description
ZNF828: Required for proper alignment of chromosomes at metaphase and their accurate segregation during mitosis. Involved in the maintenance of spindle microtubules attachment to the kinetochore during sister chromatid biorientation. May recruit CENPE and CENPF to the kinetochore.
Protein type: C2H2-type zinc finger protein; RNA-binding
Chromosomal Location of Human Ortholog: 13q34
Cellular Component: condensed chromosome; nucleoplasm; nucleus; spindle
Molecular Function: protein binding
Biological Process: attachment of spindle microtubules to kinetochore during mitosis; sister chromatid biorientation
Disease: Mental Retardation, Autosomal Dominant 40
Research Articles on CHAMP1
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Product Notes
The CHAMP1 champ1 (Catalog #AAA9417285) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The CHAMP1 Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's CHAMP1 can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC). Immunohistochemistry: 1: 20-100. Researchers should empirically determine the suitability of the CHAMP1 champ1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CHAMP1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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