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Immunohistochemistry (IHC) (Anti-CGB/hCG Beta antibody IHC staining of human placenta. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.)

Sheep anti-Human CGB/hCG Beta Polyclonal Antibody | anti-CGB antibody

Anti-CGB/hCG Beta Antibody

Gene Names
CGB3; CGB; CGB5; CGB7; CGB8; hCGB
Reactivity
Human
Applications
ELISA, Immunohistochemistry, immunoassay, Radioimmunoassay
Purity
Protein G purified
Synonyms
CGB/hCG Beta; Polyclonal Antibody; Anti-CGB/hCG Beta Antibody; Goat Polyclonal (IgG) to Human CGB/hCG Beta; CGB; CGB3; CG-beta; Choriogonadotropin beta chain; HCGB; hCG Beta; anti-CGB antibody
Ordering
For Research Use Only!
Host
Sheep
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Specificity
The beta subunit of human chorionic gonadotrophin (hCG) and recognizes both the free subunit and the whole molecule. Negligible reactivity has been observed with hLH, hTSH and hFSH. Human chorionic gonadotrophin is a peptide hormone produced by placental syncytiotrophoblasts. It acts to maintain the corpus luteum until the developing placenta is able to produce the required levels of estrogen and progesterone. hCG shares a common alpha chain with the pituitary hormones FSH, TSH and LH, but has a unique beta chain which is recognized by this.
Purity/Purification
Protein G purified
Form/Format
PBS, pH 7.2, 0.09% sodium azide.
Sequence Length
165
Applicable Applications for anti-CGB antibody
ELISA (EIA), Immunohistochemistry (IHC) Paraffin, Radioimmunoassay (RIA)
Application Notes
IHC-P: 5 ug/ml
Immunogen
Native, from urine.
Conjugation
Unconjugated
Preparation and Storage
Short term storage: 4 degree C
Long term storage: aliquot and store at -20 degree C, avoid freeze thaw cycles.
Store undiluted.

Immunohistochemistry (IHC)

(Anti-CGB/hCG Beta antibody IHC staining of human placenta. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.)

Immunohistochemistry (IHC) (Anti-CGB/hCG Beta antibody IHC staining of human placenta. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.)
Related Product Information for anti-CGB antibody
CGB/hCG Beta is a member of the glycoprotein hormone beta chainfamily and encodes the beta 3 subunit of chorionic gonadotropin (CG).Glycoprotein hormones are heterodimers consisting of a common alpha subunit and an unique beta subunit which confers biological specificity.CG is produced by the trophoblastic cells of the placenta and stimulates the ovaries to synthesize the steroids that are essential forthe maintenance of pregnancy.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
19,053 Da
NCBI Official Full Name
choriogonadotropin subunit beta 3
NCBI Official Synonym Full Names
chorionic gonadotropin subunit beta 3
NCBI Official Symbol
CGB3
NCBI Official Synonym Symbols
CGB; CGB5; CGB7; CGB8; hCGB
NCBI Protein Information
choriogonadotropin subunit beta 3
UniProt Protein Name
Choriogonadotropin subunit beta 3
Protein Family
UniProt Gene Name
CGB3
UniProt Synonym Gene Names
CGB; CG-beta

NCBI Description

This gene is a member of the glycoprotein hormone beta chain family and encodes the beta 3 subunit of chorionic gonadotropin (CG). Glycoprotein hormones are heterodimers consisting of a common alpha subunit and an unique beta subunit which confers biological specificity. CG is produced by the trophoblastic cells of the placenta and stimulates the ovaries to synthesize the steroids that are essential for the maintenance of pregnancy. The beta subunit of CG is encoded by 6 genes which are arranged in tandem and inverted pairs on chromosome 19q13.3 and contiguous with the luteinizing hormone beta subunit gene. [provided by RefSeq, Jul 2008]

Uniprot Description

Beta subunit of the human chorionic gonadotropin (hCG). hCG is a complex glycoprotein composed of two glycosylated subunits alpha and beta which are non-covalently associated. The alpha subunit is identical to those in the pituitary gonadotropin hormones (LH, FSH and TSH). The beta subunits are distinct in each of the hormones and confer receptor and biological specificity. Has an essential role in pregnancy and maternal adaptation. Stimulates the ovaries to synthesize the steroids that are essential for the maintenance of pregnancy.

Research Articles on CGB

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Product Notes

The CGB cgb3 (Catalog #AAA2400825) is an Antibody produced from Sheep and is intended for research purposes only. The product is available for immediate purchase. The Anti-CGB/hCG Beta Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's CGB/hCG Beta can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Immunohistochemistry (IHC) Paraffin, Radioimmunoassay (RIA). IHC-P: 5 ug/ml. Researchers should empirically determine the suitability of the CGB cgb3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CGB/hCG Beta, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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