Rabbit anti-Human CGB Polyclonal Antibody | anti-CGB antibody

CGB

Cat. Num. AAA127922

• Reactivity: Human
• Applications: Western Blot, Immunohistochemistry
• Purity: Affinity purification
• Synonyms: CGB; Polyclonal Antibody; CGB3; CGB5; CGB7; CGB8; hCGB; anti-CGB antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: Affinity purification
• Form/Format: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
• Sequence Length: 165

• Applicable Applications for anti-CGB antibody: Western Blot (WB), Immunohistochemistry (IHC)
• Application Notes: WB: 1:500-1:2000; IHC: 1:50-1:200
• Immunogen: Recombinant protein of human CGB.

Western Blot (WB)

(Western blot analysis of extracts of various cell lines, using CGB Antibody at 1:500 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (MBS128200) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit.Exposure time: 60s.)

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded human stomach using CGB antibody at dilution of 1:100 (40x lens).)

Related Product Information for anti-CGB antibody

This gene is a member of the glycoprotein hormone beta chain family and encodes the beta 3 subunit of chorionic gonadotropin (CG). Glycoprotein hormones are heterodimers consisting of a common alpha subunit and an unique beta subunit which confers biological specificity. CG is produced by the trophoblastic cells of the placenta and stimulates the ovaries to synthesize the steroids that are essential for the maintenance of pregnancy. The beta subunit of CG is encoded by 6 genes which are arranged in tandem and inverted pairs on chromosome 19q13.3 and contiguous with the luteinizing hormone beta subunit gene.

Product Categories/Family for anti-CGB antibody

Polyclonal

NCBI and Uniprot Product Information

• NCBI GI #: 116184
• NCBI GeneID: 1082
• UniProt Accession #: P0DN86; Q13991; Q14000; Q3KPI3; Q3SY41; Q8WTT5; Q8WXL1; Q8WXL2; Q8WXL3; Q8WXL4; A1A5E0; B9ZVP5
• Molecular Weight: Calculated MW: 18 kDa; Observed MW: 18 kDa
• NCBI Official Full Name: Choriogonadotropin subunit beta
• NCBI Official Synonym Full Names: chorionic gonadotropin, beta polypeptide 8
• NCBI Official Symbol: CGB8
• NCBI Protein Information: chorionic gonadotropin, beta polypeptide 8; chorionic gonadotropin beta 8 subunit
• UniProt Protein Name: Choriogonadotropin subunit beta
• Protein Family: Choriogonadotropin
• UniProt Gene Name: CGB
• UniProt Synonym Gene Names: CGB3; CG-beta
• UniProt Entry Name: CGHB_HUMAN

NCBI Description

This gene is a member of the glycoprotein hormone beta chain family and encodes the beta 8 subunit of chorionic gonadotropin (CG). Glycoprotein hormones are heterodimers consisting of a common alpha subunit and an unique beta subunit which confers biological specificity. CG is produced by the trophoblastic cells of the placenta and stimulates the ovaries to synthesize the steroids that are essential for the maintenance of pregnancy. The beta subunit of CG is encoded by 6 genes which are arranged in tandem and inverted pairs on chromosome 19q13.3 and contiguous with the luteinizing hormone beta subunit gene. [provided by RefSeq, Jul 2008]

Uniprot Description

CGB: Stimulates the ovaries to synthesize the steroids that are essential for the maintenance of pregnancy. Belongs to the glycoprotein hormones subunit beta family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Inhibitor; Secreted, signal peptide; Secreted

Chromosomal Location of Human Ortholog: 19q13.32

Cellular Component: extracellular region

Molecular Function: hormone activity

Biological Process: cellular protein metabolic process; cell-cell signaling; apoptosis; peptide hormone processing; female gamete generation; signal transduction