Loading...

Skip to main content

Call us on + 1 (800) 604-9114 for more information about our products

Looking for specific datasheet Manual/COA/MSDS?
Request a Manual/COA/MSDS

Interested to get a quote about our products?
Request a Quote

Western Blot (WB) (Western blotAll lanes: CFL2 antibody at 3.75ug/mlLane 1: Mouse brain tissueLane 2: Mouse liver tissueLane 3: Mouse lung tissueLane 4: LO2 whole cell lysateLane 5: Hela whole cell lysateLane 6: A549 whole cell lysateGoat polyclonal to Rabbit IgG at 1/10000 dilutionPredicted band size: 19,17 kDaObserved band size: 19 kDa)

Rabbit anti-Human, Mouse CFL2 Polyclonal Antibody | anti-CFL2 antibody

CFL2 Antibody

Reactivity
Human, Mouse
Applications
ELISA, Western Blot, Immunohistochemistry
Purity
Antigen Affinity Purified
Synonyms
CFL2; Polyclonal Antibody; CFL2 Antibody; Cofilin-2; Cofilin; muscle isoform; anti-CFL2 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Mouse
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Antigen Affinity Purified
Form/Format
Liquid
Sequence Length
149
Applicable Applications for anti-CFL2 antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
Species
Human
Immunogen
Recombinant human Cofilin-2 protein (1-166AA)
Conjugate
Non-conjugated
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Santa Cruz Alternative
Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-32160
Preparation and Storage
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.

Western Blot (WB)

(Western blotAll lanes: CFL2 antibody at 3.75ug/mlLane 1: Mouse brain tissueLane 2: Mouse liver tissueLane 3: Mouse lung tissueLane 4: LO2 whole cell lysateLane 5: Hela whole cell lysateLane 6: A549 whole cell lysateGoat polyclonal to Rabbit IgG at 1/10000 dilutionPredicted band size: 19,17 kDaObserved band size: 19 kDa)

Western Blot (WB) (Western blotAll lanes: CFL2 antibody at 3.75ug/mlLane 1: Mouse brain tissueLane 2: Mouse liver tissueLane 3: Mouse lung tissueLane 4: LO2 whole cell lysateLane 5: Hela whole cell lysateLane 6: A549 whole cell lysateGoat polyclonal to Rabbit IgG at 1/10000 dilutionPredicted band size: 19,17 kDaObserved band size: 19 kDa)

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded human skeletal muscle tissue using MBS7045271 at dilution 1:100)

Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded human skeletal muscle tissue using MBS7045271 at dilution 1:100)

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded human heart tissue using MBS7045271 at dilution 1:100)

Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded human heart tissue using MBS7045271 at dilution 1:100)
Related Product Information for anti-CFL2 antibody
Controls reversibly actin polymerization and depolymerization in a pH-sensitive manner. Its F-actin depolymerization activity is regulated by association with CSPR3 (PubMed:19752190). It has the ability to bind G- and F-actin in a 1:1 ratio of cofilin to actin. It is the major component of intranuclear and cytoplasmic actin rods. Required for muscle maintenance. May play a role during the exchange of alpha-actin forms during the early postnatal remodeling of the sarcomere (By similarity).

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
– Da
NCBI Official Full Name
cofilin-2 isoform 2
UniProt Protein Name
Cofilin-2
Protein Family
UniProt Gene Name
CFL2
UniProt Entry Name
COF2_HUMAN

Uniprot Description

Cofilin-2: a cytoskeletal protein that controls actin depolymerization. Has a 5-10-fold higher affinity for ATP-actin monomers than cofilin-1. May promote filament assembly rather than disassembly. Two alternatively spliced variants are described. Isoform b is expressed predominantly in skeletal muscle and heart, while isoform a is expressed in various tissues.

Protein type: Cytoskeletal; Motility/polarity/chemotaxis; Nuclear receptor co-regulator

Chromosomal Location of Human Ortholog: 14q12

Cellular Component: extracellular space; I band

Molecular Function: protein binding

Biological Process: positive regulation of actin filament depolymerization

Disease: Nemaline Myopathy 7

Similar Products

Product Notes

The CFL2 cfl2 (Catalog #AAA7045271) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The CFL2 Antibody reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's CFL2 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC). Researchers should empirically determine the suitability of the CFL2 cfl2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CFL2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

Item has been added to Shopping Cart

If you are ready to order, navigate to Shopping Cart and get ready to checkout.

Looking for a specific manual?
Request a Manual

Request more Information

Please complete the form below and a representative will contact you as soon as possible.

Request a Manual

Please complete the form below and a representative will contact you as soon as possible.

Request a Quote

Please complete the form below and a representative will contact you as soon as possible.