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Western Blot (WB) (Western Blot (WB) analysis of CEP170 polyclonal antibody at 1:500 dilutionLane1:L02 whole cell lysate (40ug) Lane2:HEK293T whole cell lysate (40ug) Lane3:A549 whole cell lysate (40ug))

Rabbit anti-Human CEP170 Polyclonal Antibody | anti-CEP170 antibody

CEP170 Polyclonal Antibody

Reactivity
Human
Applications
Western Blot
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is >95% (by SDS-PAGE).
Synonyms
CEP170; Polyclonal Antibody; CEP170 Polyclonal Antibody; Centrosomal protein of 170 kDa; Cep170; KARP-1-binding protein; KARP1-binding protein; FAM68A; KAB; KIAA0470; anti-CEP170 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Specificity
CEP170 polyclonal antibody detects endogenous levels of CEP170 protein.
Purity/Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is >95% (by SDS-PAGE).
Form/Format
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Sequence Length
1486
Applicable Applications for anti-CEP170 antibody
Western Blot (WB)
Application Notes
WB: 1:500-1:1000
Immunogen
Synthetic peptide, corresponding Human CEP170.
Preparation and Storage
Store at 4 degree C short term.
Aliquot and store at -20 degree C long term.
Avoid freeze-thaw cycles.

Western Blot (WB)

(Western Blot (WB) analysis of CEP170 polyclonal antibody at 1:500 dilutionLane1:L02 whole cell lysate (40ug) Lane2:HEK293T whole cell lysate (40ug) Lane3:A549 whole cell lysate (40ug))

Western Blot (WB) (Western Blot (WB) analysis of CEP170 polyclonal antibody at 1:500 dilutionLane1:L02 whole cell lysate (40ug) Lane2:HEK293T whole cell lysate (40ug) Lane3:A549 whole cell lysate (40ug))
Related Product Information for anti-CEP170 antibody
Centrosomal protein 170kDa, also known as CEP170, is a protein that in humans is encoded by the CEP170 geneThe product of this gene is a component of the centrosome, a non-membraneous organelle that functions as the major microtubule-organizing center in animal cells. During interphase, the encoded protein localizes to the sub-distal appendages of mature centrioles, which are microtubule-based structures thought to help organize centrosomes. During mitosis, the protein associates with spindle microtubules near the centrosomes. The protein interacts with the intraflagellar transport protein 81 (IFT81), the SH3-domain containing protein PRAX-1, and is phosphorylated by cyclin dependent kinase 1 (Cdk1) and polo-like kinase 1 (PLK1), and functions in maintaining Microtubule organization, cell morphology and cilium stability.

NCBI and Uniprot Product Information

NCBI GI #
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
~ 175kDa
NCBI Official Full Name
centrosomal protein of 170 kDa isoform beta
UniProt Protein Name
Centrosomal protein of 170 kDa
Protein Family
UniProt Gene Name
CEP170
UniProt Synonym Gene Names
FAM68A; KAB; KIAA0470; Cep170
UniProt Entry Name
CE170_HUMAN

Uniprot Description

CEP170: a centrosomal protein containing a forkhead associated (FHA) domain. Interacts with Polo-like kinase 1 (PLK1), binds microtubules, and is involved in bundling microtubules.

Protein type: Cell cycle regulation

Chromosomal Location of Human Ortholog: 1q44

Cellular Component: centriole; centrosome; microtubule; nuclear membrane; cytoplasm; spindle

Molecular Function: protein binding

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Product Notes

The CEP170 cep170 (Catalog #AAA3007558) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The CEP170 Polyclonal Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's CEP170 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). WB: 1:500-1:1000. Researchers should empirically determine the suitability of the CEP170 cep170 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CEP170, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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