Loading...

Skip to main content

Call us on + 1 (800) 604-9114 for more information about our products

Looking for specific datasheet Manual/COA/MSDS?
Request a Manual/COA/MSDS

Interested to get a quote about our products?
Request a Quote

SDS-Page (Gel: 6%SDS-PAGE lysate: 40 ¦Œg, Lane: PC-3 cell lysate, Primary antibody: 46474£¨CEP170 Antibody) at dilution 1/350 Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 1 minute)

Rabbit anti-Human CEP170 Polyclonal Antibody | anti-CEP170 antibody

CEP170 Antibody

Gene Names
CEP170; KAB; FAM68A; KIAA0470
Reactivity
Human
Applications
Western Blot, Immunohistochemistry
Purity
Antigen affinity purification
Synonyms
CEP170; Polyclonal Antibody; CEP170 Antibody; KAB; FAM68A; KIAA0470; anti-CEP170 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Specificity
The antibody detects endogenous levels of total CEP170 protein.
Purity/Purification
Antigen affinity purification
Form/Format
In pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
Concentration
0.8mg/ml (varies by lot)
Sequence Length
1584
Applicable Applications for anti-CEP170 antibody
Western Blot (WB), Immunohistochemistry (IHC)
Application Notes
WB: 1:200-1:1000
IHC: 1: 10-50
Immunogen
Synthetic peptide corresponding to residues near the C terminal of human CEP170
Immunogen Type
Peptide
Preparation and Storage
Store at -20 degree C.

SDS-Page

(Gel: 6%SDS-PAGE lysate: 40 ¦Œg, Lane: PC-3 cell lysate, Primary antibody: 46474£¨CEP170 Antibody) at dilution 1/350 Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 1 minute)

SDS-Page (Gel: 6%SDS-PAGE lysate: 40 ¦Œg, Lane: PC-3 cell lysate, Primary antibody: 46474£¨CEP170 Antibody) at dilution 1/350 Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 1 minute)

Immunohistochemistry (IHC)

(The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using 46474(CEP170 Antibody) at dilution 1/25, on the right is treated with synthetic peptide. (Original magnification: x200))

Immunohistochemistry (IHC) (The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using 46474(CEP170 Antibody) at dilution 1/25, on the right is treated with synthetic peptide. (Original magnification: x200))
Related Product Information for anti-CEP170 antibody
The product of this gene is a component of the centrosome, a non-membraneous organelle that functions as the major microtubule-organizing center in animal cells. During interphase, the encoded protein localizes to the sub-distal appendages of mature centrioles, which are microtubule-based structures thought to help organize centrosomes. During mitosis, the protein associates with spindle microtubules near the centrosomes. The protein interacts with and is phosphorylated by polo-like kinase 1, and functions in maintaining microtubule organization and cell morphology. The human genome contains a putative transcribed pseudogene. Several alternatively spliced transcript variants of this gene have been found, but the full-length nature of some of these variants has not been determined.
Product Categories/Family for anti-CEP170 antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
175 kDa
NCBI Official Full Name
centrosomal protein of 170 kDa isoform alpha
NCBI Official Synonym Full Names
centrosomal protein 170
NCBI Official Symbol
CEP170
NCBI Official Synonym Symbols
KAB; FAM68A; KIAA0470
NCBI Protein Information
centrosomal protein of 170 kDa
UniProt Protein Name
Centrosomal protein of 170 kDa
Protein Family
UniProt Gene Name
CEP170
UniProt Synonym Gene Names
FAM68A; KAB; KIAA0470; Cep170; KARP1-binding protein

NCBI Description

The product of this gene is a component of the centrosome, a non-membraneous organelle that functions as the major microtubule-organizing center in animal cells. During interphase, the encoded protein localizes to the sub-distal appendages of mature centrioles, which are microtubule-based structures thought to help organize centrosomes. During mitosis, the protein associates with spindle microtubules near the centrosomes. The protein interacts with and is phosphorylated by polo-like kinase 1, and functions in maintaining microtubule organization and cell morphology. The human genome contains a putative transcribed pseudogene. Several alternatively spliced transcript variants of this gene have been found, but the full-length nature of some of these variants has not been determined. [provided by RefSeq, Jul 2008]

Uniprot Description

Plays a role in microtubule organization (PubMed:15616186). Required for centriole subdistal appendage assembly (PubMed:28422092).

Research Articles on CEP170

Similar Products

Product Notes

The CEP170 cep170 (Catalog #AAA9429621) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The CEP170 Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's CEP170 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC). WB: 1:200-1:1000 IHC: 1: 10-50. Researchers should empirically determine the suitability of the CEP170 cep170 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CEP170, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

Item has been added to Shopping Cart

If you are ready to order, navigate to Shopping Cart and get ready to checkout.

Looking for a specific manual?
Request a Manual

Request more Information

Please complete the form below and a representative will contact you as soon as possible.

Request a Manual

Please complete the form below and a representative will contact you as soon as possible.

Request a Quote

Please complete the form below and a representative will contact you as soon as possible.