Rabbit anti-Human CEP104 Polyclonal Antibody | anti-CEP104 antibody

CEP104 Antibody

Cat. Num. AAA9429620

• Gene Names: CEP104; GlyBP; ROC22; JBTS25; CFAP256; KIAA0562
• Reactivity: Human
• Applications: Immunohistochemistry
• Purity: Antigen affinity purification
• Synonyms: CEP104; Polyclonal Antibody; CEP104 Antibody; GlyBP; ROC22; JBTS25; CFAP256; KIAA0562; anti-CEP104 antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Isotype: IgG
• Specificity: The antibody detects endogenous levels of total CEP104 protein.
• Purity/Purification: Antigen affinity purification
• Form/Format: In pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
• Concentration: 0.8mg/ml (varies by lot)
• Sequence Length: 925

• Applicable Applications for anti-CEP104 antibody: Immunohistochemistry (IHC)
• Application Notes: IHC: 1: 25-100
• Immunogen: Synthetic peptide corresponding to internal residues of human CEP104
• Immunogen Type: Peptide
• Preparation and Storage: Store at -20 degree C.

Immunohistochemistry (IHC)

(The image on the left is immunohistochemistry of paraffin-embedded Human colorectal cancer tissue using 46473(CEP104 Antibody) at dilution 1/25, on the right is treated with synthetic peptide. (Original magnification: x200))

Immunohistochemistry (IHC)

(The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using 46473(CEP104 Antibody) at dilution 1/25, on the right is treated with synthetic peptide. (Original magnification: x200))

Related Product Information for anti-CEP104 antibody

This gene encodes a centrosomal protein required for ciliogenesis and for ciliary tip structural integrity. The mammalian protein contains three amino-terminal hydrophobic domains, two glycosylation sites, four cysteine-rich motifs, and two regions with homology to the glutamate receptor ionotropic, NMDA 1 protein. During ciliogenesis, the encoded protein translocates from the distal tips of the centrioles to the tip of the elongating cilium. Knockdown of the protein in human retinal pigment cells results in severe defects in ciliogenesis with structural deformities at the ciliary tips. Allelic variants of this gene are associated with the autosomal-recessive disorder Joubert syndrome, which is characterized by a distinctive mid-hindbrain and cerebellar malformation, oculomotor apraxia, irregular breathing, developmental delay, and ataxia.

Product Categories/Family for anti-CEP104 antibody

Total protein Ab

NCBI and Uniprot Product Information

• NCBI GI #: 7662180
• NCBI GeneID: 9731
• NCBI Accession #: NP_055519
• NCBI GenBank Nucleotide #: NM_014704.3
• UniProt Accession #: O60308; Q5JSQ3; Q5SR24; Q5SR25; Q6PKF5; Q86W32; Q86X14; A0A024R4G3
• Molecular Weight: 63,187 Da
• NCBI Official Full Name: centrosomal protein of 104 kDa
• NCBI Official Synonym Full Names: centrosomal protein 104
• NCBI Official Symbol: CEP104
• NCBI Official Synonym Symbols: GlyBP; ROC22; JBTS25; CFAP256; KIAA0562
• NCBI Protein Information: centrosomal protein of 104 kDa
• UniProt Protein Name: Centrosomal protein of 104 kDa
• Protein Family: Centrosomal protein
• UniProt Gene Name: CEP104
• UniProt Synonym Gene Names: KIAA0562; Cep104

NCBI Description

This gene encodes a centrosomal protein required for ciliogenesis and for ciliary tip structural integrity. The mammalian protein contains three amino-terminal hydrophobic domains, two glycosylation sites, four cysteine-rich motifs, and two regions with homology to the glutamate receptor ionotropic, NMDA 1 protein. During ciliogenesis, the encoded protein translocates from the distal tips of the centrioles to the tip of the elongating cilium. Knockdown of the protein in human retinal pigment cells results in severe defects in ciliogenesis with structural deformities at the ciliary tips. Allelic variants of this gene are associated with the autosomal-recessive disorder Joubert syndrome, which is characterized by a distinctive mid-hindbrain and cerebellar malformation, oculomotor apraxia, irregular breathing, developmental delay, and ataxia. [provided by RefSeq, Feb 2016]

Uniprot Description

Required for ciliogenesis and for structural integrity at the ciliary tip.