Western Blot (WB)
(Western blot analysis of extracts of various cell lines, using CEMIP antibody.)
Rabbit anti-Human, Mouse CEMIP Polyclonal Antibody | anti-CEMIP antibody
CEMIP Polyclonal Antibody
Gene Names
CEMIP; CCSP1; HYBID; TMEM2L; KIAA1199
Reactivity
Human, Mouse
Applications
Western Blot
Purity
Affinity Purification
Synonyms
CEMIP; Polyclonal Antibody; CEMIP Polyclonal Antibody; IR2155535; KIAA1199 protein; OTTHUMP00000185569; OTTHUMP00000195036; TMEM2L; Transmembrane protein 2 like; anti-CEMIP antibody
Host
Rabbit
Reactivity
Human, Mouse
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Affinity Purification
Form/Format
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Concentration
1 mg/mL (varies by lot)
Sequence Length
992
Applicable Applications for anti-CEMIP antibody
Western Blot (WB)
Application Notes
WB: 1:200-1:2000
Immunogen
Recombinant protein of human CEMIP
Conjugation
Unconjugated
Preparation and Storage
Store at -20 degree C. Avoid freeze/thaw cycles.
Western Blot (WB)
(Western blot analysis of extracts of various cell lines, using CEMIP antibody.)
Western Blot (WB)
(Western blot analysis of extracts of various cell lines, using CEMIP antibody.)
Related Product Information for anti-CEMIP antibody
KIAA1199, also known as CEMIP, was first discovered as an inner-ear protein whose genetic mutations were linked to nonsyndromic hearing loss. KIAA1199 is involved in hyaluronan degradation. Studies have shown that KIAA1199 is overexpressed in many types of cancers, suggesting a critical role of KIAA1199 in cancer progression.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
Calculated: 110kDa; 152kDa
Observed: 180kDa
Observed: 180kDa
NCBI Official Full Name
cell migration-inducing and hyaluronan-binding protein
NCBI Official Synonym Full Names
cell migration inducing hyaluronidase 1
NCBI Official Symbol
CEMIP
NCBI Official Synonym Symbols
CCSP1; HYBID; TMEM2L; KIAA1199
NCBI Protein Information
cell migration-inducing and hyaluronan-binding protein
UniProt Protein Name
Cell migration-inducing and hyaluronan-binding protein
Protein Family
UniProt Gene Name
CEMIP
UniProt Synonym Gene Names
KIAA1199
Uniprot Description
Mediates depolymerization of hyaluronic acid (HA) via the cell membrane-associated clathrin-coated pit endocytic pathway. Binds to hyaluronic acid. Hydrolyzes high molecular weight hyaluronic acid to produce an intermediate-sized product, a process that may occur through rapid vesicle endocytosis and recycling without intracytoplasmic accumulation or digestion in lysosomes. Involved in hyaluronan catabolism in the dermis of the skin and arthritic synovium. Positively regulates epithelial-mesenchymal transition (EMT), and hence tumor cell growth, invasion and cancer dissemination. In collaboration with HSPA5/BIP, promotes cancer cell migration in a calcium and PKC-dependent manner. May be involved in hearing.
Research Articles on CEMIP
Similar Products
Product Notes
The CEMIP cemip (Catalog #AAA2555962) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The CEMIP Polyclonal Antibody reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's CEMIP can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). WB: 1:200-1:2000. Researchers should empirically determine the suitability of the CEMIP cemip for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CEMIP, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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