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Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded Mouse colon using Ceacam1 Polycloanl Antibody at dilution of 1:200)

Rabbit anti-Mouse, Rat CEACAM1 Polyclonal Antibody | anti-CEACAM1 antibody

CEACAM1 Polyclonal Antibody

Gene Names
Ceacam1; Bgp; Cc1; Hv2; Bgp1; Cea1; Cea7; Hv-2; MHVR; bb-1; C-CAM; CD66a; Cea-1; Cea-7; MHVR1; Mhv-1; mCEA1; mmCGM1; mmCGM2; mmCGM1a
Reactivity
Mouse, Rat
Applications
Immunohistochemistry
Purity
Antigen Affinity Purification
Synonyms
CEACAM1; Polyclonal Antibody; CEACAM1 Polyclonal Antibody; Antigen CD66; BGP 1; BGP; BGP-1; BGPI; Biliary glycoprotein 1; Biliary glycoprotein adhesion molecule; Biliary glycoprotein; Carcinoembryonic antigen related cell adhesion molecule 1; carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein); Carcinoembryonic antigen-related cell adhesion molecule 1; CD66a; CD66a antigen; CEAM1; meconium antigen 100; anti-CEACAM1 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Antigen Affinity Purification
Form/Format
PBS with 0.05% Proclin300, 50% glycerol, pH7.3.
Concentration
1mg/mL (varies by lot)
Sequence Length
521
Applicable Applications for anti-CEACAM1 antibody
Immunohistochemistry (IHC)
Application Notes
IHC: 1:100-1:300
Immunogen
Recombinant Mouse Carcinoembryonic antigen-related cell adhesion molecule 1 protein
Conjugation
Unconjugated
Preparation and Storage
Store at -20?. Avoid freeze/ thaw cycles.

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded Mouse colon using Ceacam1 Polycloanl Antibody at dilution of 1:200)

Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded Mouse colon using Ceacam1 Polycloanl Antibody at dilution of 1:200)

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded Mouse liver using Ceacam1 Polycloanl Antibody at dilution of 1:200)

Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded Mouse liver using Ceacam1 Polycloanl Antibody at dilution of 1:200)

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded Rat liver using Ceacam1 Polycloanl Antibody at dilution of 1:200)

Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded Rat liver using Ceacam1 Polycloanl Antibody at dilution of 1:200)
Related Product Information for anti-CEACAM1 antibody
This gene encodes a member of the carcinoembryonic antigen (CEA) gene family, which belongs to the immunoglobulin superfamily. Two subgroups of the CEA family, the CEA cell adhesion molecules and the pregnancy-specific glycoproteins, are located within a 1.2 Mb cluster on the long arm of chromosome 19. Eleven pseudogenes of the CEA cell adhesion molecule subgroup are also found in the cluster. The encoded protein was originally described in bile ducts of liver as biliary glycoprotein. Subsequently, it was found to be a cell-cell adhesion molecule detected on leukocytes, epithelia, and endothelia. The encoded protein mediates cell adhesion via homophilic as well as heterophilic binding to other proteins of the subgroup.
Product Categories/Family for anti-CEACAM1 antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
NCBI Official Full Name
carcinoembryonic antigen-related cell adhesion molecule 1 isoform 1
NCBI Official Synonym Full Names
carcinoembryonic antigen-related cell adhesion molecule 1
NCBI Official Symbol
Ceacam1
NCBI Official Synonym Symbols
Bgp; Cc1; Hv2; Bgp1; Cea1; Cea7; Hv-2; MHVR; bb-1; C-CAM; CD66a; Cea-1; Cea-7; MHVR1; Mhv-1; mCEA1; mmCGM1; mmCGM2; mmCGM1a
NCBI Protein Information
carcinoembryonic antigen-related cell adhesion molecule 1
UniProt Protein Name
Carcinoembryonic antigen-related cell adhesion molecule 1
Protein Family
UniProt Gene Name
Ceacam1
UniProt Synonym Gene Names
BGP-1; MHV-R

Uniprot Description

CEACAM1: carcinoembryonic antigen-related cell adhesion molecule 1. A cell-cell adhesion molecule that directly associates with annexin II. Has tumor suppressor activity in prostate carcinoma. Belongs to the immunoglobulin superfamily and the CEA family. Abundantly expressed in epithelia, vessel endothelia, trophoblasts, platelets and neutrophilic granulocytes. Also present in many cell types of the immune system such as B cells, T cells, NK cells, macrophages and dendritic cells. Five alternatively spliced isoforms have been described. Two isoforms are type I membrane proteins, while three are secreted.

Protein type: Cell adhesion; Immunoglobulin superfamily; Membrane protein, integral; Motility/polarity/chemotaxis

Chromosomal Location of Human Ortholog: 7 A3|7 13.84 cM

Cellular Component: adherens junction; apical plasma membrane; basal plasma membrane; brush border membrane; cell junction; cell projection; cell surface; cytoplasmic vesicle; external side of plasma membrane; extracellular exosome; extracellular space; integral component of membrane; intercellular junction; lateral plasma membrane; membrane; plasma membrane; T cell receptor complex

Molecular Function: actin binding; bile acid transmembrane transporter activity; calmodulin binding; filamin binding; granulocyte colony-stimulating factor receptor binding; kinase binding; protein binding; protein dimerization activity; protein homodimerization activity; protein kinase binding; protein phosphatase binding; viral receptor activity; virion binding

Biological Process: blood vessel development; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules; calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules; cell-cell junction organization; entry of virus into host cell; granulocyte colony-stimulating factor signaling pathway; homophilic cell adhesion; insulin catabolic process; negative regulation by host of viral process; negative regulation of bone resorption; negative regulation of cytokine production; negative regulation of granulocyte differentiation; negative regulation of hepatocyte proliferation; negative regulation of interleukin-1 production; negative regulation of interleukin-2 production; negative regulation of JNK cascade; negative regulation of lipid biosynthetic process; negative regulation of natural killer cell mediated cytotoxicity directed against tumor cell target; negative regulation of osteoclast differentiation; negative regulation of platelet aggregation; negative regulation of protein kinase activity; negative regulation of T cell proliferation; negative regulation of vascular permeability; Peyer's patch development; positive regulation by host of viral process; positive regulation of CD4-positive, alpha-beta T cell activation; positive regulation of CD4-positive, alpha-beta T cell proliferation; positive regulation of CD8-positive, alpha-beta T cell activation; positive regulation of immunoglobulin secretion; positive regulation of JNK cascade; positive regulation of MAP kinase activity; positive regulation of NFAT protein import into nucleus; positive regulation of T cell proliferation; positive regulation of vasculogenesis; regulation of endothelial cell differentiation; regulation of endothelial cell migration; regulation of epidermal growth factor receptor signaling pathway; viral process

Research Articles on CEACAM1

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Product Notes

The CEACAM1 ceacam1 (Catalog #AAA2563551) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The CEACAM1 Polyclonal Antibody reacts with Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's CEACAM1 can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC). IHC: 1:100-1:300. Researchers should empirically determine the suitability of the CEACAM1 ceacam1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CEACAM1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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