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Western Blot (WB) (Western blot analysis of CDO1 in rat liver tissue lysate with CDO1 antibody at (A) 1 and (B) 2 μg/ml.)

Rabbit CDO1 Polyclonal Antibody | anti-CDO1 antibody

CDO1 Antibody

Reactivity
Human, Mouse, Rat
Applications
ELISA, Western Blot
Purity
CDO1 antibody is affinity chromatography purified via peptide column.
Synonyms
CDO1; Polyclonal Antibody; CDO1 Antibody; Cysteine dioxygenase type I; CDO; CDO-I; Cysteine dioxygenase type 1; anti-CDO1 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Specificity
CDO1 antibody is human, mouse and rat reactive.
Purity/Purification
CDO1 antibody is affinity chromatography purified via peptide column.
Form/Format
Liquid
Concentration
1 mg/mL (varies by lot)
Sequence Length
200
Applicable Applications for anti-CDO1 antibody
ELISA (EIA), Western Blot (WB)
Application Notes
CDO1 antibody can be used for detection of CDO1 by Western blot at 1 - 2 mug/ml.
Conjugate
Unconjugated
Immunogen
CDO1 antibody was raised against a 19 amino acid peptide near the amino terminus of human CDO1.
Buffer
CDO1 antibody is supplied in PBS containing 0.02% sodium azide.
Preparation and Storage
CDO1 antibody can be stored at 4 degree C for three months and -20 degree C, stable for up to one year.

Western Blot (WB)

(Western blot analysis of CDO1 in rat liver tissue lysate with CDO1 antibody at (A) 1 and (B) 2 μg/ml.)

Western Blot (WB) (Western blot analysis of CDO1 in rat liver tissue lysate with CDO1 antibody at (A) 1 and (B) 2 μg/ml.)
Related Product Information for anti-CDO1 antibody
CDO1 (cysteine dioxygenase, type I) belongs to the cysteine dioxygenase family and is involved in organosulfur biosynthesis (1). CDO1 functions as a dioxygenase that uses iron and zinc as cofactors to catalyze the conversion of L-cysteine and oxygen to 3-sulfinoalanine (1,2). CDO1 exists as a monomer and is expressed at high levels in liver and placenta and at lower levels in brain, pancreas and heart (1). CDO1 is involved in pyruvate-, sulfate- and taurine-related metabolic pathways and is a crucial regulator of cysteine concentrations within the cell (3,4).

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
Predicted: 22 kDa

Observed: 24 kDa
NCBI Official Full Name
cysteine dioxygenase type 1
NCBI Official Synonym Full Names
cysteine dioxygenase type 1
NCBI Official Symbol
CDO1
NCBI Protein Information
cysteine dioxygenase type 1; CDO; CDO-I; cysteine dioxygenase, type I
UniProt Protein Name
Cysteine dioxygenase type 1
Protein Family
UniProt Gene Name
CDO1
UniProt Synonym Gene Names
CDO; CDO-I
UniProt Entry Name
CDO1_HUMAN

Uniprot Description

CDO1: Initiates several important metabolic pathways related to pyruvate and several sulfurate compounds including sulfate, hypotaurine and taurine. Critical regulator of cellular cysteine concentrations. Has an important role in maintaining the hepatic concentation of intracellular free cysteine within a proper narrow range. Belongs to the cysteine dioxygenase family.

Protein type: Amino Acid Metabolism - cysteine and methionine; Other Amino Acids Metabolism - taurine and hypotaurine; EC 1.13.11.20; Oxidoreductase

Chromosomal Location of Human Ortholog: 5q23.2

Cellular Component: cytosol

Molecular Function: cysteine dioxygenase activity; ferrous iron binding

Biological Process: lactation; response to glucagon stimulus; sulfur amino acid biosynthetic process; response to cAMP; sulfur amino acid catabolic process; response to glucocorticoid stimulus; response to amino acid stimulus; cysteine metabolic process; response to ethanol; sulfur amino acid metabolic process; taurine biosynthetic process; inflammatory response; L-cysteine catabolic process

Research Articles on CDO1

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Product Notes

The CDO1 cdo1 (Catalog #AAA153581) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The CDO1 Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's CDO1 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB). CDO1 antibody can be used for detection of CDO1 by Western blot at 1 - 2 mug/ml. Researchers should empirically determine the suitability of the CDO1 cdo1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CDO1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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