Western Blot (WB)
(Western blot analysis of CDK8 expression in HepG2 (A); A549 (B); Raw264.7 (C) whole cell lysates.)
Rabbit CDK8 Polyclonal Antibody | anti-CDK8 antibody
CDK8 Antibody
Gene Names
CDK8; K35
Applications
Western Blot, Immunohistochemistry
Purity
Immunogen Affinity Chromatography
Synonyms
CDK8; Polyclonal Antibody; CDK8 Antibody; Purified Polyclonal CDK8 Antibody; Polyclonal CDK8 antibody; Anti-CDK8 antibody; Cyclin-dependent kinase 8 antibody; Cell division protein kinase 8 antibody; Mediator complex subunit CDK8 antibody; Mediator of RNA polymerase II transcription subunit CDK8 antibody; Protein kinase K35 antibody; anti-CDK8 antibody
Host
Rabbit
Clonality
Polyclonal
Specificity
Recognizes endogenous levels of CDK8 protein
Purity/Purification
Immunogen Affinity Chromatography
Form/Format
Supplied in liquid form in 0.42% Potassium Phosphate, 0.87% Sodium Chloride, pH 7.3 with 30% Glycerol and 0.01% Sodium Azide
Sequence Length
464
Applicable Applications for anti-CDK8 antibody
Western Blot (WB), Immunohistochemistry (IHC)
Application Notes
WB: 1:500-1:1000
IHC: 1:100-1:200
IHC: 1:100-1:200
Immunogen
CDK8 antibody was raised in Rabbit using a KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human CDK8 as the immunogen
Cross-Reactivity
Mouse, Rat
Preparation and Storage
Store at 4 degree C for short term storage. For long term, aliquot and store at -20 degree C. Avoid repeat freeze/thaw cycles.
Western Blot (WB)
(Western blot analysis of CDK8 expression in HepG2 (A); A549 (B); Raw264.7 (C) whole cell lysates.)
Western Blot (WB)
(Western blot analysis of CDK8 expression in HepG2 (A); A549 (B); Raw264.7 (C) whole cell lysates.)
Related Product Information for anti-CDK8 antibody
CDK8 is a member of the cyclin-dependent protein kinase (CDK) family. CDK family members are highly similar to the gene products of Saccharomyces cerevisiae cdc28, and Schizosaccharomyces pombe cdc2, and are known to be important regulators of cell cycle progression.
Product Categories/Family for anti-CDK8 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Official Full Name
CDK8 protein kinase
NCBI Official Synonym Full Names
cyclin dependent kinase 8
NCBI Official Symbol
CDK8
NCBI Official Synonym Symbols
K35
NCBI Protein Information
cyclin-dependent kinase 8
Protein Family
NCBI Description
This gene encodes a member of the cyclin-dependent protein kinase (CDK) family. CDK family members are known to be important regulators of cell cycle progression. This kinase and its regulatory subunit, cyclin C, are components of the Mediator transcriptional regulatory complex, involved in both transcriptional activation and repression by phosphorylation of the carboxy-terminal domain of the largest subunit of RNA polymerase II. This kinase regulates transcription by targeting the cyclin-dependent kinase 7 subunits of the general transcription initiation factor IIH, thus providing a link between the Mediator complex and the basal transcription machinery. Multiple pseudogenes of this gene have been identified. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2016]
Research Articles on CDK8
Similar Products
Product Notes
The CDK8 (Catalog #AAA5316107) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's CDK8 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC). WB: 1:500-1:1000 IHC: 1:100-1:200. Researchers should empirically determine the suitability of the CDK8 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CDK8, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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