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Western Blot (WB) (Western blot analysis CdGAP (Phospho-Thr789) using Insulin treated HeLa whole cell lysates)

Rabbit CdGAP Polyclonal Antibody | anti-CdGAP antibody

CdGAP (Phospho-Thr789) Antibody

Gene Names
ARHGAP31; AOS1; CDGAP
Reactivity
Human, Mouse, Rat
Applications
Western Blot
Synonyms
CdGAP; Polyclonal Antibody; CdGAP (Phospho-Thr789) Antibody; anti-CdGAP antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Specificity
CdGAP (Phospho-Thr789) Antibody detects endogenous levels of CdGAP only when phosphorylated at Thr789
Form/Format
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration
1 mg/ml (varies by lot)
Sequence Length
1444
Applicable Applications for anti-CdGAP antibody
Western Blot (WB)
Application Notes
Western Blot: 1:1000
Immunogen
A synthesized peptide derived from human CdGAP (Phospho-Thr789)
Immunogen Type
Peptide
Target Species
Human
Modification
Phospho-Thr789
Purification
Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.
Preparation and Storage
Store at -20 degree C

Western Blot (WB)

(Western blot analysis CdGAP (Phospho-Thr789) using Insulin treated HeLa whole cell lysates)

Western Blot (WB) (Western blot analysis CdGAP (Phospho-Thr789) using Insulin treated HeLa whole cell lysates)
Product Categories/Family for anti-CdGAP antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
157kd
NCBI Official Full Name
rho GTPase-activating protein 31
NCBI Official Synonym Full Names
Rho GTPase activating protein 31
NCBI Official Symbol
ARHGAP31
NCBI Official Synonym Symbols
AOS1; CDGAP
NCBI Protein Information
rho GTPase-activating protein 31
UniProt Protein Name
Rho GTPase-activating protein 31
UniProt Gene Name
ARHGAP31
UniProt Synonym Gene Names
CDGAP; KIAA1204
UniProt Entry Name
RHG31_HUMAN

NCBI Description

This gene encodes a GTPase-activating protein (GAP). A variety of cellular processes are regulated by Rho GTPases which cycle between an inactive form bound to GDP and an active form bound to GTP. This cycling between inactive and active forms is regulated by guanine nucleotide exchange factors and GAPs. The encoded protein is a GAP shown to regulate two GTPases involved in protein trafficking and cell growth. [provided by RefSeq, Jul 2008]

Uniprot Description

CdGAP: Functions as a GTPase-activating protein (GAP) for RAC1 and CDC42. Required for cell spreading, polarized lamellipodia formation and cell migration. Interacts with ITSN1, which inhibits GAP activity. Interacts with PARVA. Interacts with GTP-loaded RHOU.

Protein type: GAPs; GAPs, Rac/Rho

Chromosomal Location of Human Ortholog: 3q13.33

Cellular Component: cytosol; lamellipodium

Molecular Function: GTPase activator activity

Biological Process: regulation of small GTPase mediated signal transduction; small GTPase mediated signal transduction

Disease: Adams-oliver Syndrome 1

Research Articles on CdGAP

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Product Notes

The CdGAP arhgap31 (Catalog #AAA9416671) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The CdGAP (Phospho-Thr789) Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's CdGAP can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). Western Blot: 1:1000. Researchers should empirically determine the suitability of the CdGAP arhgap31 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CdGAP, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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