Immunohistochemistry (IHC)
(Immunochemical staining of mouse Cdc25b in mouse kidney with rabbit polyclonal antibody at 1:200 dilution, formalin-fixed paraffin embedded sections.)
Rabbit Cdc25B Polyclonal Antibody | anti-CDC25B antibody
Anti-Cdc25B Antibody, Rabbit Polyclonal
Gene Names
Cdc25b; AI604853
Reactivity
MousePredicted to React with: Human (Species predicted to react based on 100% sequence homology)
Applications
Immunohistochemistry
Purity
Protein A & Antigen Affinity
Synonyms
Cdc25B; Polyclonal Antibody; Anti-Cdc25B Antibody; Rabbit Polyclonal; Cdc25B Antibody; Rabbit PAb; Antigen Affinity Purified; anti-CDC25B antibody
Host
Rabbit
Reactivity
Mouse
Predicted to React with: Human (Species predicted to react based on 100% sequence homology)
Predicted to React with: Human (Species predicted to react based on 100% sequence homology)
Clonality
Polyclonal
Isotype
Rabbit IgG
Specificity
Mouse Cdc25B
Purity/Purification
Protein A & Antigen Affinity
Form/Format
Liquid; PBS, pH7.0 with 0.03% Proclin300
Applicable Applications for anti-CDC25B antibody
Immunohistochemistry-Paraffin (IHC-P)
Application Notes
IHC-P: 1:100-1:400
Immunogen
A synthetic peptide corresponding to the C-terminus of the Mouse Cdc25B
Conjugation
Unconjugated
Preparation
Produced in rabbits immunized with a synthetic peptide corresponding to the C-terminus of the Mouse Cdc25B, and purified by antigen affinity chromatography.
Preparation and Storage
This antibody can be stored at 2-8 degree C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20 degree C to -80 degree C. Avoid repeated freeze-thaw cycles.
Immunohistochemistry (IHC)
(Immunochemical staining of mouse Cdc25b in mouse kidney with rabbit polyclonal antibody at 1:200 dilution, formalin-fixed paraffin embedded sections.)
Immunohistochemistry (IHC)
(Immunochemical staining of mouse Cdc25b in mouse kidney with rabbit polyclonal antibody at 1:200 dilution, formalin-fixed paraffin embedded sections.)
Related Product Information for anti-CDC25B antibody
CDC25 phosphatases are key cell cycle regulators and represent very attractive but challenging targets for anticancer drug discovery. CDC25B may be used as a potential prognostic marker in the pathogenesis of retinoblastoma. In mitosis, Kiz is a new substrate of CDC25B whose dephosphorylation following CDC25B stabilization leads to the formation of multipolar spindles. Furthermore, endogenous Kiz and CDC25B interact only in mitosis, suggesting that Kiz phosphorylation depends on a balance between CDC25B and Plk1 activities. The abnormal expression of CDC25B phosphatases detected in a number of tumors implies that their dysregulation is involved in malignant transformation. Both CDC25B and PED/PEA-15 play a certain role in the carcinogenesis of esophageal cancer, they will be the new /therapeutic targets in esophageal carcinoma.
Product Categories/Family for anti-CDC25B antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
65,490 Da
NCBI Official Full Name
M-phase inducer phosphatase 2 isoform a
NCBI Official Synonym Full Names
cell division cycle 25B
NCBI Official Symbol
Cdc25b
NCBI Official Synonym Symbols
AI604853
NCBI Protein Information
M-phase inducer phosphatase 2; dual specificity phosphatase Cdc25B
UniProt Protein Name
M-phase inducer phosphatase 2
UniProt Gene Name
Cdc25b
UniProt Synonym Gene Names
Cdc25m2
UniProt Entry Name
MPIP2_MOUSE
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Product Notes
The CDC25B cdc25b (Catalog #AAA8102519) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-Cdc25B Antibody, Rabbit Polyclonal reacts with Mouse Predicted to React with: Human (Species predicted to react based on 100% sequence homology) and may cross-react with other species as described in the data sheet. AAA Biotech's Cdc25B can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry-Paraffin (IHC-P). IHC-P: 1:100-1:400. Researchers should empirically determine the suitability of the CDC25B cdc25b for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Cdc25B, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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