Rabbit anti-Human CD5L Polyclonal Antibody

CD5L (CD5 Antigen-like, CT-2, IgM-associated Peptide, SP-alpha, API6, UNQ203/PRO229)

Cat. Num. AAA6009233

• Reactivity: Human
• Applications: Western Blot
• Purity: Affinity Purified; Purified by Protein A affinity chromatography.
• Synonyms: CD5L; Polyclonal Antibody; CD5L (CD5 Antigen-like; CT-2; IgM-associated Peptide; SP-alpha; API6; UNQ203/PRO229); Anti -CD5L (CD5 Antigen-like; anti-CD5L antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Isotype: IgG
• Specificity: Recognizes human CD5L.
• Purity/Purification: Affinity Purified; Purified by Protein A affinity chromatography.
• Form/Format: Supplied as a liquid in PBS, pH 7.2.
• Sequence: MALLFSLILAICTRPGFLASPSGVRLVGGLHRCEGRVEVEQKGQWGTVCDDGWDIKDVAVLCRELGCGAASGTPSGILYEPPAEKEQKVLIQSVSCTGTEDTLAQCEQEEVYDCSHDEDAGASCENPESSFSPVPEGVRLADGPGHCKGRVEVKHQNQWYTVCQTGWSLRAAKVVCRQLGCGRAVLTQKRCNKHAYGRKPIWLSQMSCSGREATLQDCPSGPWGKNTCNHDEDTWVECEDPFDLRLVGGDNLCSGRLEVLHKGVWGSVCDDNWGEKEDQVVCKQLGCGKSLSPSFRDRKCYGPGVGRIWLDNVRCSGEEQSLEQCQHRFWGFHDCTHQEDVAVICSG

• Applicable Applications for anti-CD5L antibody: Western Blot (WB)
• Application Notes: Suitable for use in Western Blot.
• Immunogen: Full length human CD5L, aa1-347 (NP_005885.1).
• Preparation and Storage: May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Western Blot (WB)

(Western Blot analysis of CD5L expression in transfected 293T cell line by CD5L polyclonal antibody. Lane 1: CD5L transfected lysate (38.1kD). Lane 2: Non-transfected lysate.)

Related Product Information for anti-CD5L antibody

CD5L is a member of the scavenger receptor cysteine-rich domain superfamily (SRCR-SF) initially identified as an inducible cell surface ligand of CD5. It was shown that CD5L functions in the thymus as the inducer of resistance to apoptosis within CD4+/CD8+ thymocytes and as the supporter of the viability of these cells before thymic selection. CD5L was also shown to support macrophage survival and enhance their phagocytic function. More recent experiments using recombinant CD5L significantly inhibited apoptosis of NKT and T cells obtained from C. parvum-stimulated livers in vitro, suggesting that CD5L functions to induce resistance to apoptosis in these cells and supports host defense against inflammation during infection.

Product Categories/Family for anti-CD5L antibody

Antibodies; Abs to CD Markers

NCBI and Uniprot Product Information

• NCBI GI #: 37182111
• NCBI Official Full Name: CD5L
• Protein Family: CD5 antigen

Uniprot Description

CD5L: May play a role in the regulation of the immune system. Seems to play a role as an inhibitor of apoptosis.

Protein type: Secreted; Receptor, misc.; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 1q23.1

Cellular Component: extracellular space; membrane; extracellular region

Molecular Function: scavenger receptor activity

Biological Process: receptor-mediated endocytosis; apoptosis; cellular defense response