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Sheep anti-Mouse CD39L3 Polyclonal Antibody | anti-ENTPD3 antibody

CD39L3 (CD39-like 3, Ectonucleoside Triphosphate Diphosphohydrolase-3, eNTPDase 3, HB6) (Biotin)

Gene Names
ENTPD3; HB6; CD39L3; FLJ93839; NTPDase-3
Reactivity
Mouse
Applications
Western Blot
Purity
Affinity Purified
Purified by immunoaffinity chromatography.
Synonyms
CD39L3; Polyclonal Antibody; CD39L3 (CD39-like 3; Ectonucleoside Triphosphate Diphosphohydrolase-3; eNTPDase 3; HB6) (Biotin); Anti -CD39L3 (CD39-like 3; anti-ENTPD3 antibody
Ordering
For Research Use Only!
Host
Sheep
Reactivity
Mouse
Clonality
Polyclonal
Isotype
IgG
Specificity
Recognizes mouse CD39L3.
Purity/Purification
Affinity Purified
Purified by immunoaffinity chromatography.
Form/Format
Supplied as a lyophilized powder in Tris, pH 7.3, 1% BSA. Reconstitute with 1ml sterile 40-50% glycerol, Tris, 0.1mg/ml BSA. Labeled with Biotin.
Applicable Applications for anti-ENTPD3 antibody
Western Blot (WB)
Application Notes
Suitable for use in Western Blot.
Dilution: Western Blot: 0.1-0.2ug/ml detection limit for rmCD39L3 is ~5ng/lane under non-reducing and reducing conditions. Optimal dilutions to be determined by the researcher.
Immunogen
CHO cell-derived rmCD39L3, (aa44-485)
Preparation and Storage
Lyophilized powder may be stored at -20 degree C. Reconstitute to nominal volume by adding sterile 40-50% glycerol, aliquot and store at -20 degree C. Reconstituted product is stable for 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Related Product Information for anti-ENTPD3 antibody
CD39L3 (CD39-like 3, Ectonucleoside Triphosphate Diphosphohydrolase-3, eNTPDase 3, HB6) is an 80kD, class I member of the GDA1/CD39 NTPase family of transmembrane (TM) enzymes. It is a cell-surface glycoprotein that hydrolyses both extracellular ATP and ADP. Thus, it controls ATP activation of P2X ion channel purinoreceptors. Mouse CD39L3 is 529 amino acids (aa) in length. It contains two TM segments plus an N- and C-terminal cytoplasmic region. Based on human CD39L3, the mouse extracellular domain (ECD) will contain aa 44-485. Within the ECD, mouse CD39L3 shares 82% and 94% aa identity with human and rat CD39L3 ECD, respectively.
Product Categories/Family for anti-ENTPD3 antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
956
UniProt Accession #
Molecular Weight
59,105 Da
NCBI Official Full Name
CD39L3
NCBI Official Synonym Full Names
ectonucleoside triphosphate diphosphohydrolase 3
NCBI Official Symbol
ENTPD3
NCBI Official Synonym Symbols
HB6; CD39L3; FLJ93839; NTPDase-3
NCBI Protein Information
ectonucleoside triphosphate diphosphohydrolase 3; NTPDase 3; CD39-like 3; ecto-ATPase 3; ecto-ATPDase 3; ecto-apyrase 3; OTTHUMP00000162079; OTTHUMP00000209227; OTTHUMP00000209228; CD39 antigen-like 3; ecto-ATP diphosphohydrolase 3
UniProt Protein Name
Ectonucleoside triphosphate diphosphohydrolase 3
UniProt Gene Name
ENTPD3
UniProt Synonym Gene Names
CD39L3
UniProt Entry Name
ENTP3_HUMAN

NCBI Description

ENTPD3 is similar to E-type nucleotidases (NTPases). NTPases, such as CD39, mediate catabolism of extracellular nucleotides. ENTPD3 contains 4 apyrase-conserved regions which is characteristic of NTPases. [provided by RefSeq]

Uniprot Description

ENTPD3: Has a threefold preference for the hydrolysis of ATP over ADP. Belongs to the GDA1/CD39 NTPase family.

Protein type: Nucleotide Metabolism - pyrimidine; Nucleotide Metabolism - purine; Membrane protein, multi-pass; Phosphatase (non-protein); Membrane protein, integral; EC 3.6.1.5; Hydrolase

Chromosomal Location of Human Ortholog: 3p21.3

Cellular Component: integral to membrane; plasma membrane

Molecular Function: nucleoside-diphosphatase activity; nucleoside-triphosphatase activity; ATP binding

Biological Process: nucleoside diphosphate catabolic process; nucleoside triphosphate catabolic process

Research Articles on ENTPD3

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Product Notes

The ENTPD3 entpd3 (Catalog #AAA610804) is an Antibody produced from Sheep and is intended for research purposes only. The product is available for immediate purchase. The CD39L3 (CD39-like 3, Ectonucleoside Triphosphate Diphosphohydrolase-3, eNTPDase 3, HB6) (Biotin) reacts with Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's CD39L3 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). Suitable for use in Western Blot. Dilution: Western Blot: 0.1-0.2ug/ml detection limit for rmCD39L3 is ~5ng/lane under non-reducing and reducing conditions. Optimal dilutions to be determined by the researcher. Researchers should empirically determine the suitability of the ENTPD3 entpd3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CD39L3, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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