Western Blot (WB)
(Western blot analysis of rat kidney tissue lysate probed with Rabbit anti CD268 / BAFF-R antibody)
Rabbit anti-Mouse CD268/BAFF-R Polyclonal Antibody | anti-CD268/BAFF-R antibody
RABBIT ANTI CD268 / BAFF-R
Shelf Life: 12 months from date of despatch
Western Blot (WB)
(Western blot analysis of rat kidney tissue lysate probed with Rabbit anti CD268 / BAFF-R antibody)
Western Blot (WB)
(Western blot analysis of rat kidney tissue lysate probed with Rabbit anti CD268 / BAFF-R antibody)
NCBI and Uniprot Product Information
Uniprot Description
BAFF-R: B-cell receptor specific for TNFSF13B/TALL1/BAFF/BLyS. Promotes the survival of mature B-cells and the B-cell response. Defects in TNFRSF13C are the cause of immunodeficiency common variable type 4 (CVID4); also called antibody deficiency due to BAFFR defect. CVID4 is a primary immunodeficiency characterized by antibody deficiency, hypogammaglobulinemia, recurrent bacterial infections and an inability to mount an antibody response to antigen. The defect results from a failure of B-cell differentiation and impaired secretion of immunoglobulins; the numbers of circulating B-cells is usually in the normal range, but can be low. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Membrane protein, integral; Receptor, misc.; Cell cycle regulation; Cell surface
Cellular Component: external side of plasma membrane; integral to membrane; membrane
Biological Process: adaptive immune response; B cell costimulation; B cell homeostasis; immune system process; positive regulation of B cell proliferation; positive regulation of germinal center formation; positive regulation of interferon-gamma biosynthetic process; positive regulation of T cell proliferation; regulation of immune response; T cell costimulation
Research Articles on CD268/BAFF-R
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Product Notes
The CD268/BAFF-R tnfrsf13c (Catalog #AAA224864) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The RABBIT ANTI CD268 / BAFF-R reacts with Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's CD268/BAFF-R can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). Western Blot: 0.5; 4.0 ug/ml. Researchers should empirically determine the suitability of the CD268/BAFF-R tnfrsf13c for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CD268/BAFF-R, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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