Typical Testing Data/Standard Curve (for reference only)
(Mouse TNFRSF13C/BAFFR PicoKine ELISA Kit standard curve )
Mouse TNFRSF13C/BAFFR ELISA Kit | TNFRSF13C elisa kit
Mouse TNFRSF13C/BAFFR PicoKine ELISA Kit
Gene Names
Tnfrsf13c; Bcmd; Baffr; Bcmd1; BAFF-R; Bcmd-1; Lvis22; 2010006P15Rik
Reactivity
Mouse
Synonyms
TNFRSF13C/BAFFR; Mouse TNFRSF13C/BAFFR PicoKine ELISA Kit; Tumor necrosis factor receptor superfamily member 13C; tumor necrosis factor receptor superfamily; member 13C; B Cell Activating Factor Receptor; B-cell-activating factor receptor; BAFF R; BAFF receptor; BAFF-R; BAFFR; BLyS receptor 3; BlySR3; BR 3; BR3; BROMIX; CD 268; CD268; CD268 antigen; CVID4; MGC138235; OTTHUMP00000028746; Prolixin; TNFRSF 13C; TNFRSF13C; TR13C_HUMAN; Tumor Necrosis Factor Receptor Subunit Member 13C; TNFRSF13C elisa kit
Reactivity
Mouse
Specificity
Natural and recombinant mouse TNFRSF13C
Sequence Length
175
Samples
Cell culture supernates, serum and plasma (heparin, EDTA)
Assay Type
Sandwich
Detection Range
78pg/ml-5000pg/ml
Sensitivity
< 10pg/ml
Intra-assay Precision
Intra-Assay Precision (Precision within an assay) Three samples of known concentration were tested on one plate to assess intra-assay precision.
Inter-assay Precision
Inter-Assay Precision (Precision between assays) Three samples of known concentration were tested in separate assays to assess inter-assay precision.
Preparation and Storage
Store at 4 degree C for 6 months, at -20 degree C for 12 months. Avoid multiple freeze-thaw cycles (Shipped with wet ice.)
Typical Testing Data/Standard Curve (for reference only)
(Mouse TNFRSF13C/BAFFR PicoKine ELISA Kit standard curve )
Typical Testing Data/Standard Curve (for reference only)
(Mouse TNFRSF13C/BAFFR PicoKine ELISA Kit standard curve )
Related Product Information for TNFRSF13C elisa kit
Principle of the assay: mouse TNFRSF13C ELISA Kit was based on standard sandwich enzyme-linked immune-sorbent assay technology. A monoclonal antibody from rat specific for TNFRSF13C has been precoated onto 96-well plates. Standards(NSO, S10-A71) and test samples are added to the wells, a biotinylated detection polyclonal antibody from goat specific for TNFRSF13C is added subsequently and then followed by washing with PBS or TBS buffer. Avidin-Biotin-Peroxidase Complex was added and unbound conjugates were washed away with PBS or TBS buffer. HRP substrate TMB was used to visualize HRP enzymatic reaction. TMB was catalyzed by HRP to produce a blue color product that changed into yellow after adding acidic stop solution. The density of yellow is proportional to the mouse TNFRSF13C amount of sample captured in plate.
Background: Tumor necrosis factor receptor superfamily member 13C also known as B-cell-activating factor receptor or BAFF receptor is a protein that in humans is encoded by the TNFRSF13C gene. By homology to a BAC clone, the BAFFR gene was mapped to chromosome 22q13.1-q13.31. B-cell activating factor (BAFF) enhances B-cell survival in vitro and is a regulator of the peripheral B-cell population. The protein encoded by this gene is a receptor for BAFF and is a type III transmembrane protein containing a single extracellular phenylalanine-rich domain. It is thought that this receptor is the principal receptor required for BAFF-mediated mature B-cell survival.
Background: Tumor necrosis factor receptor superfamily member 13C also known as B-cell-activating factor receptor or BAFF receptor is a protein that in humans is encoded by the TNFRSF13C gene. By homology to a BAC clone, the BAFFR gene was mapped to chromosome 22q13.1-q13.31. B-cell activating factor (BAFF) enhances B-cell survival in vitro and is a regulator of the peripheral B-cell population. The protein encoded by this gene is a receptor for BAFF and is a type III transmembrane protein containing a single extracellular phenylalanine-rich domain. It is thought that this receptor is the principal receptor required for BAFF-mediated mature B-cell survival.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
UniProt Accession #
Molecular Weight
17,576 Da
NCBI Official Full Name
Tumor necrosis factor receptor superfamily member 13C
NCBI Official Synonym Full Names
tumor necrosis factor receptor superfamily, member 13c
NCBI Official Symbol
Tnfrsf13c
NCBI Official Synonym Symbols
Bcmd; Baffr; Bcmd1; BAFF-R; Bcmd-1; Lvis22; 2010006P15Rik
NCBI Protein Information
tumor necrosis factor receptor superfamily member 13C; BAFF receptor; BLyS receptor 3; B-cell maturation defect 1; B-cell-activating factor receptor; b cell-activating factor receptor
UniProt Protein Name
Tumor necrosis factor receptor superfamily member 13C
Protein Family
UniProt Gene Name
Tnfrsf13c
UniProt Synonym Gene Names
Baffr; Bcmd; Br3; BAFF-R
UniProt Entry Name
TR13C_MOUSE
Uniprot Description
BAFF-R: B-cell receptor specific for TNFSF13B/TALL1/BAFF/BLyS. Promotes the survival of mature B-cells and the B-cell response. Defects in TNFRSF13C are the cause of immunodeficiency common variable type 4 (CVID4); also called antibody deficiency due to BAFFR defect. CVID4 is a primary immunodeficiency characterized by antibody deficiency, hypogammaglobulinemia, recurrent bacterial infections and an inability to mount an antibody response to antigen. The defect results from a failure of B-cell differentiation and impaired secretion of immunoglobulins; the numbers of circulating B-cells is usually in the normal range, but can be low. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Receptor, misc.; Cell cycle regulation; Membrane protein, integral; Cell surface
Cellular Component: membrane; integral to membrane; external side of plasma membrane
Biological Process: B cell costimulation; regulation of immune response; B cell homeostasis; immune system process; T cell costimulation; positive regulation of B cell proliferation; positive regulation of germinal center formation; positive regulation of T cell proliferation; positive regulation of interferon-gamma biosynthetic process
Research Articles on TNFRSF13C
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Product Notes
The Mouse TNFRSF13C tnfrsf13c (Catalog #AAA177212) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA177212 ELISA Kit recognizes Mouse TNFRSF13C. It is sometimes possible for the material contained within the vial of "TNFRSF13C/BAFFR, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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