Western Blot (WB)
(WB Suggested Anti-CD226 AntibodyTitration: 1.0 ug/mlPositive Control: RPMI-8226 Whole Cell)
Rabbit CD226 Polyclonal Antibody | anti-CD226 antibody
CD226 antibody - C-terminal region
Western Blot (WB)
(WB Suggested Anti-CD226 AntibodyTitration: 1.0 ug/mlPositive Control: RPMI-8226 Whole Cell)
Western Blot (WB)
(WB Suggested Anti-CD226 AntibodyTitration: 1.0 ug/mlPositive Control: RPMI-8226 Whole Cell)
Target Description: This gene encodes a glycoprotein expressed on the surface of NK cells, platelets, monocytes and a subset of T cells. It is a member of the Ig-superfamily containing 2 Ig-like domains of the V-set. The protein mediates cellular adhesion of platelets and megakaryocytic cells to vascular endothelial cells. The protein also plays a role in megakaryocytic cell maturation.
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a glycoprotein expressed on the surface of NK cells, platelets, monocytes and a subset of T cells. It is a member of the Ig-superfamily containing 2 Ig-like domains of the V-set. The protein mediates cellular adhesion of platelets and megakaryocytic cells to vascular endothelial cells. The protein also plays a role in megakaryocytic cell maturation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2015]
Uniprot Description
DNAM-1: Receptor involved in intercellular adhesion, lymphocyte signaling, cytotoxicity and lymphokine secretion mediated by cytotoxic T-lymphocyte (CTL) and NK cell.
Protein type: Cell adhesion; Immunoglobulin superfamily; Membrane protein, integral
Chromosomal Location of Human Ortholog: 18q22.3
Cellular Component: cell surface; integral to plasma membrane; plasma membrane; external side of plasma membrane; lipid raft
Molecular Function: integrin binding; protein binding; cell adhesion molecule binding; protein kinase binding
Biological Process: regulation of immune response; positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target; positive regulation of immunoglobulin mediated immune response; cytokine production; cell recognition; cell adhesion; positive regulation of natural killer cell mediated cytotoxicity; signal transduction; positive regulation of mast cell activation
Research Articles on CD226
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Product Notes
The CD226 cd226 (Catalog #AAA3216156) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The CD226 antibody - C-terminal region reacts with Guinea Pig, Horse, Human, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's CD226 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). Researchers should empirically determine the suitability of the CD226 cd226 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: Synthetic peptide located within the following region: ISITTIIVIF LNRRRRRERR DLFTESWDTQ KAPNNYRSPI STSQPTNQSM. It is sometimes possible for the material contained within the vial of "CD226, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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