Rabbit anti-Human CD163 Polyclonal Antibody | anti-CD163 antibody
CD163 (M130, MM130, Hemoglobin scavenger receptor) (Biotin)
Gene Names
CD163; M130; MM130; SCARI1
Reactivity
Human
Applications
Western Blot, Immunohistochemistry
Purity
Purified by Immunoaffinity chromatography.
Synonyms
CD163; Polyclonal Antibody; CD163 (M130; MM130; Hemoglobin scavenger receptor) (Biotin); anti-CD163 antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Specificity
Recognizes human CD163. No crossreactivity with other proteins.
Purity/Purification
Purified by Immunoaffinity chromatography.
Form/Format
Supplied as a liquid in PBS, pH 7.2. Labeled with Biotin.
Sequence Length
1156
Applicable Applications for anti-CD163 antibody
Western Blot (WB), Immunohistochemistry (IHC) Paraffin
Application Notes
Applications are based on unconjugated antibody.
Immunogen
E. coli-derived human CD163 recombinant protein (Position: F1056-L1165).
Conjugate
Biotin
Note
Preservative Free
Preparation and Storage
Store at -20 degree C for one year. After reconstitution, store at 4 degree C for one month. Can also be aliquoted and stored frozen at -20 degree C for long term.
Product Categories/Family for anti-CD163 antibody
References
1. Fabriek, B. O., van Bruggen, R., Deng, D. M., Ligtenberg, A. J. M., Nazmi, K., Schornagel, K., Vloet, R. P. M., Dijkstra, C. D., van den Berg, T. K. The macrophage scavenger receptor CD163 functions as an innate immune sensor for bacteria. Blood 113: 887-892, 2009. 2. Ritter, M., Buechler, C., Langmann, T., Schmitz, G.Genomic organization and chromosomal localization of the human CD163 (M130) gene: a member of the scavenger receptor cysteine-rich superfamily. Biochem. Biophys. Res. Commun. 260: 466-474, 1999. 3. Stover, C. M., Schleypen, J., Gronlund, J., Speicher, M. R., Schwaeble, W. J., Holmskov, U. Assignment of CD163B, the gene encoding M160, a novel scavenger receptor, to human chromosome 12p13. 3 by in situ hybridization and somatic cell hybrid analysis. Cytogenet. Cell Genet. 90: 246-247, 2000.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
UniProt Accession #
NCBI Official Full Name
Scavenger receptor cysteine-rich type 1 protein M130
NCBI Official Synonym Full Names
CD163 molecule
NCBI Official Symbol
CD163
NCBI Official Synonym Symbols
M130; MM130; SCARI1
NCBI Protein Information
scavenger receptor cysteine-rich type 1 protein M130
Protein Family
NCBI Description
The protein encoded by this gene is a member of the scavenger receptor cysteine-rich (SRCR) superfamily, and is exclusively expressed in monocytes and macrophages. It functions as an acute phase-regulated receptor involved in the clearance and endocytosis of hemoglobin/haptoglobin complexes by macrophages, and may thereby protect tissues from free hemoglobin-mediated oxidative damage. This protein may also function as an innate immune sensor for bacteria and inducer of local inflammation. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Aug 2011]
Research Articles on CD163
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Product Notes
The CD163 (Catalog #AAA6404206) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The CD163 (M130, MM130, Hemoglobin scavenger receptor) (Biotin) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's CD163 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC) Paraffin. Applications are based on unconjugated antibody. Researchers should empirically determine the suitability of the CD163 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CD163, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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