Western Blot (WB)
(Gel: 8%SDS-PAGE Lysate: 40 μ g Lane 1-2: Hela cell and mouse brain tissue Primary antibody: 1/400 dilution Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution Exposure time: 5 seconds)
Rabbit anti-Human, Mouse CCT5 Polyclonal Antibody | anti-CCT5 antibody
CCT5 Antibody
Immunohistochemistry: 1:20-1:100
Western Blot (WB)
(Gel: 8%SDS-PAGE Lysate: 40 μ g Lane 1-2: Hela cell and mouse brain tissue Primary antibody: 1/400 dilution Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution Exposure time: 5 seconds)
Western Blot (WB)
(Gel: 8%SDS-PAGE Lysate: 40 μ g Lane 1-2: Hela cell and mouse brain tissue Primary antibody: 1/400 dilution Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution Exposure time: 5 seconds)
Immunohistochemistry (IHC)
(Immunohistochemical analysis of paraffin-embedded Human prostate cancer tissue using at dilution 1/20. (Original magnification: ¡200))
Immunohistochemistry (IHC)
(Immunohistochemical analysis of paraffin-embedded Human prostate cancer tissue using at dilution 1/20. (Original magnification: ¡200))
NCBI and Uniprot Product Information
Uniprot Description
CCT5: Molecular chaperone; assists the folding of proteins upon ATP hydrolysis. As part of the BBS/CCT complex may play a role in the assembly of BBSome, a complex involved in ciliogenesis regulating transports vesicles to the cilia. Known to play a role, in vitro, in the folding of actin and tubulin. Defects in CCT5 are the cause of hereditary sensory neuropathy autosomal recessive with spastic paraplegia (HSNSP). The disease is characterized by spastic paraplegia and progressive distal sensory neuropathy leading to mutilating ulcerations of the upper and lower limbs. Belongs to the TCP-1 chaperonin family.
Protein type: Chaperone
Chromosomal Location of Human Ortholog: 5p15.2
Cellular Component: centrosome; chaperonin-containing T-complex; cytoplasm; cytosol; microtubule; nucleolus
Molecular Function: beta-tubulin binding; G-protein beta-subunit binding; protein binding; unfolded protein binding
Biological Process: 'de novo' protein folding; positive regulation of telomere maintenance via telomerase; protein folding; protein stabilization; response to virus
Disease: Neuropathy, Hereditary Sensory, With Spastic Paraplegia, Autosomal Recessive
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Product Notes
The CCT5 cct5 (Catalog #AAA9416005) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The CCT5 Antibody reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's CCT5 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC). Western Blot: 1:500-1:2000 Immunohistochemistry: 1:20-1:100. Researchers should empirically determine the suitability of the CCT5 cct5 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CCT5, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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