Goat anti-Mouse CCR8 Polyclonal Antibody | anti-CCR8 antibody

CCR8 (CDw198, Chemokine Receptor 8, CC-CCR-8, C-C chemokine receptor type 8, C-C CKR-8, GPR-CY6, Chemokine receptor-like 1, TER1, CMKBRL2, CC-chemokine receptor CHEMR1, CKRL1, CMKBR8, CMKBRL2) (FITC)

Cat. Num. AAA6467854

• Gene Names: Ccr8; C-C; CCR-8; CKR-8; mCCR8; Cmkbr8; CC-CKR-8; C-C CKR-8
• Reactivity: Mouse
• Applications: Immunohistochemistry, ELISA, Western Blot
• Purity: Purified by Immunoaffinity chromatography.
• Synonyms: CCR8; Polyclonal Antibody; CCR8 (CDw198; Chemokine Receptor 8; CC-CCR-8; C-C chemokine receptor type 8; C-C CKR-8; GPR-CY6; Chemokine receptor-like 1; TER1; CMKBRL2; CC-chemokine receptor CHEMR1; CKRL1; CMKBR8; CMKBRL2) (FITC); anti-CCR8 antibody

• Host: Goat
• Reactivity: Mouse
• Clonality: Polyclonal
• Isotype: IgG
• Specificity: Recognizes mouse CCR8.
• Purity/Purification: Purified by Immunoaffinity chromatography.
• Form/Format: Supplied as a liquid in PBS, pH 7.2. Labeled with Fluorescein Isothiocyanate (FITC).

• Applicable Applications for anti-CCR8 antibody: Immunohistochemistry (IHC) Paraffin, ELISA (EIA), Western Blot (WB)
• Application Notes: IHC-P: 1:400; ELISA: 1:100,000; WB: 1:1000; Applications are based on unconjugated antibody.
• Immunogen: Synthetic peptide PNVTMTDYYPDFFTAPCDAEFLLRGSM corresponding to aa7-33 of mouse CCR8.
• Conjugate: FITC
• Positive Control: Spleen
• Note: Preservative Free
• Preparation and Storage: May be stored at 4 degree C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and store at -20 degree C. Aliquots are stable for at least 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

Immunohistochemistry (IHC)

(Paraffin embedded mouse spleen stained withMBS622694.)

Product Categories/Family for anti-CCR8 antibody

Antibodies; G Proteins

NCBI and Uniprot Product Information

• NCBI GI #: 6671774
• NCBI GeneID: 12776
• NCBI Accession #: NP_031746.1
• NCBI GenBank Nucleotide #: NM_007720.2
• UniProt Accession #: P56484
• Molecular Weight: 40,045 Da
• NCBI Official Full Name: C-C chemokine receptor type 8
• NCBI Official Synonym Full Names: chemokine (C-C motif) receptor 8
• NCBI Official Symbol: Ccr8
• NCBI Official Synonym Symbols: C-C; CCR-8; CKR-8; mCCR8; Cmkbr8; CC-CKR-8; C-C CKR-8
• NCBI Protein Information: C-C chemokine receptor type 8; C-C motif chemokine receptor 8
• UniProt Protein Name: C-C chemokine receptor type 8
• Protein Family: C-C chemokine receptor
• UniProt Gene Name: Ccr8
• UniProt Synonym Gene Names: Cmkbr8; Ter1; C-C CKR-8; CC-CKR-8; CCR-8
• UniProt Entry Name: CCR8_MOUSE

Uniprot Description

CCR8: Receptor for the chemokine CCL1/SCYA1/I-309. May regulate monocyte chemotaxis and thymic cell line apoptosis. Alternative coreceptor with CD4 for HIV-1 infection. Belongs to the G-protein coupled receptor 1 family.

Protein type: Membrane protein, integral; Motility/polarity/chemotaxis; Receptor, GPCR; Membrane protein, multi-pass; GPCR, family 1

Cellular Component: membrane; integral to membrane; plasma membrane

Molecular Function: G-protein coupled receptor activity; protein binding; signal transducer activity; C-C chemokine receptor activity; chemokine receptor activity

Biological Process: G-protein coupled receptor protein signaling pathway; elevation of cytosolic calcium ion concentration; immune response; chemotaxis; signal transduction