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Western Blot (WB) (Western blot analysis of Rat Brain cell lysates showing detection of ~41.9 kDa CCR2 protein using Rabbit Anti-CCR2 Polyclonal Antibody (SPC-704). Lane 1: Molecular Weight Ladder (MW). Lane 2: Rat Brain cell lysates. Load: 15 ug. Block: 5% Skim Milk in 1X TBST. Primary Antibody: Rabbit Anti-CCR2 Polyclonal Antibody (SPC-704) at 1:1000 for 2 hours at RT. Secondary Antibody: Goat Anti-Rabbit IgG: HRP at 1:1000 for 60 min at RT. Color Development: ECL solution for 6 min in RT. Predicted/Observed Size: ~41.9 kDa.)

Rabbit anti-Rat CCR2 Polyclonal Antibody | anti-CCR2 antibody

CCR2 Antibody: Biotin

Gene Names
CCR2; CKR2; CCR-2; CCR2A; CCR2B; CD192; CKR2A; CKR2B; CMKBR2; MCP-1-R; CC-CKR-2
Reactivity
Rat
Applications
Western Blot
Purity
Peptide Affinity Purified
Synonyms
CCR2; Polyclonal Antibody; CCR2 Antibody: Biotin; Rabbit Anti-Human CCR2 Polyclonal; CKR2 Antibody; C-C chemokine receptor type 2 Antibody; Monocyte Chemotactic Protein 1 Receptor Antibody; CC chemokine receptor type 2 Antibody; CCR1L Antibody; CCCKR2 Antibody; CD192 Antibody; MCP-1-R Antibody; MCP1 RECEPTOR Antibody; CKR2B Antibody; C-C CKR-2 Antibody; CC CKR 2 Antibody; CD_antigen: CD192 Antibody; CC-CKR-2 Antibody; CCR5L Antibody; C C chemokine receptor type 2 Antibody; CD192 antigen Antibody; CKR2A Antibody; CCR2 Antibody; Monocyte chemoattractant protein 1 receptor Antibody; CCR 2 Antibody; CCR2B Antibody; C C CKR 2 Antibody; CCR-2 Antibody; CMKBR2 Antibody; MCP 1 R Antibody; CCR2A Antibody; Chemokine CC Motif Receptor 2 Antibody; Chemokine C C motif receptor 2 Antibody; CCR2_HUMAN Antibody; MCP1R Antibody; CKR 2 Antibody; anti-CCR2 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Rat
Clonality
Polyclonal
Specificity
Detects ~42 kDa.
Purity/Purification
Peptide Affinity Purified
Concentration
1 mg/ml (varies by lot)
Sequence Length
374
Applicable Applications for anti-CCR2 antibody
Western Blot (WB)
Application Notes
WB: 1:1000
Target
CCR2
Immunogen
Synthetic peptide of Human CCR2
Immunogen Species
Human
Cellular Localization
Cell Membrane; Multi-Pass Membrane Protein
Conjugate
Biotin
Storage Buffer
PBS, 50% glycerol, 0.09% sodium azide
Preparation and Storage
Store at -20 degree C.

Western Blot (WB)

(Western blot analysis of Rat Brain cell lysates showing detection of ~41.9 kDa CCR2 protein using Rabbit Anti-CCR2 Polyclonal Antibody (SPC-704). Lane 1: Molecular Weight Ladder (MW). Lane 2: Rat Brain cell lysates. Load: 15 ug. Block: 5% Skim Milk in 1X TBST. Primary Antibody: Rabbit Anti-CCR2 Polyclonal Antibody (SPC-704) at 1:1000 for 2 hours at RT. Secondary Antibody: Goat Anti-Rabbit IgG: HRP at 1:1000 for 60 min at RT. Color Development: ECL solution for 6 min in RT. Predicted/Observed Size: ~41.9 kDa.)

Western Blot (WB) (Western blot analysis of Rat Brain cell lysates showing detection of ~41.9 kDa CCR2 protein using Rabbit Anti-CCR2 Polyclonal Antibody (SPC-704). Lane 1: Molecular Weight Ladder (MW). Lane 2: Rat Brain cell lysates. Load: 15 ug. Block: 5% Skim Milk in 1X TBST. Primary Antibody: Rabbit Anti-CCR2 Polyclonal Antibody (SPC-704) at 1:1000 for 2 hours at RT. Secondary Antibody: Goat Anti-Rabbit IgG: HRP at 1:1000 for 60 min at RT. Color Development: ECL solution for 6 min in RT. Predicted/Observed Size: ~41.9 kDa.)

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
41,064 Da
NCBI Official Full Name
C-C chemokine receptor type 2 isoform A
NCBI Official Synonym Full Names
C-C motif chemokine receptor 2
NCBI Official Symbol
CCR2
NCBI Official Synonym Symbols
CKR2; CCR-2; CCR2A; CCR2B; CD192; CKR2A; CKR2B; CMKBR2; MCP-1-R; CC-CKR-2
NCBI Protein Information
C-C chemokine receptor type 2
UniProt Protein Name
C-C chemokine receptor type 2
Protein Family
UniProt Gene Name
CCR2
UniProt Synonym Gene Names
CMKBR2; C-C CKR-2; CC-CKR-2; CCR-2; CCR2; MCP-1-R

NCBI Description

The protein encoded by this gene is a receptor for monocyte chemoattractant protein-1, a chemokine which specifically mediates monocyte chemotaxis. Monocyte chemoattractant protein-1 is involved in monocyte infiltration in inflammatory diseases such as rheumatoid arthritis as well as in the inflammatory response against tumors. The encoded protein mediates agonist-dependent calcium mobilization and inhibition of adenylyl cyclase. This protein can also be a coreceptor with CD4 for HIV-1 infection. This gene is located in the chemokine receptor gene cluster region of chromosome 3. [provided by RefSeq, Aug 2017]

Uniprot Description

Receptor for the CCL2, CCL7 and CCL13 chemokines (PubMed:23408426). Receptor for the beta-defensin DEFB106A/DEFB106B (PubMed:23938203). Transduces a signal by increasing intracellular calcium ion levels (). Upon CCL2 ligation, mediates chemotaxis and migration induction through the activation of the PI3K cascade, the small G protein Rac and lamellipodium protrusion (Probable).

Research Articles on CCR2

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Product Notes

The CCR2 ccr2 (Catalog #AAA8000258) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The CCR2 Antibody: Biotin reacts with Rat and may cross-react with other species as described in the data sheet. AAA Biotech's CCR2 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). WB: 1:1000. Researchers should empirically determine the suitability of the CCR2 ccr2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CCR2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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