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Western Blot (WB) (Western blotAll lanes: CCP110 antibody at 4.6ug/mlLane 1: Hela whole cell lysateLane 2: 293T whole cell lysateGoat polyclonal to Rabbit IgG at 1/10000 dilutionPredicted band size: 114,112 kDaObserved band size: 113 kDa)

Rabbit anti-Human CCP110 Polyclonal Antibody | anti-CCP110 antibody

CCP110 Antibody

Gene Names
CCP110; CP110; Cep110
Reactivity
Human
Applications
ELISA, Western Blot, Immunohistochemistry
Purity
Antigen Affinity Purified
Synonyms
CCP110; Polyclonal Antibody; CCP110 Antibody; Centriolar coiled-coil protein of 110 kDa; Centrosomal protein of 110 kDa; CP110; Cep110; CEP110; KIAA0419; anti-CCP110 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Antigen Affinity Purified
Form/Format
Liquid
Sequence Length
1012
Applicable Applications for anti-CCP110 antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
Species
Human
Immunogen
Recombinant human Centriolar coiled-coil protein of 110 kDa protein (N-280AA)
Conjugate
Non-conjugated
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Santa Cruz Alternative
Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-136629 / sc-136630
Preparation and Storage
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.

Western Blot (WB)

(Western blotAll lanes: CCP110 antibody at 4.6ug/mlLane 1: Hela whole cell lysateLane 2: 293T whole cell lysateGoat polyclonal to Rabbit IgG at 1/10000 dilutionPredicted band size: 114,112 kDaObserved band size: 113 kDa)

Western Blot (WB) (Western blotAll lanes: CCP110 antibody at 4.6ug/mlLane 1: Hela whole cell lysateLane 2: 293T whole cell lysateGoat polyclonal to Rabbit IgG at 1/10000 dilutionPredicted band size: 114,112 kDaObserved band size: 113 kDa)

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded human testis tissue using MBS7044697 at dilution 1:100)

Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded human testis tissue using MBS7044697 at dilution 1:100)

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded human rectum tissue using MBS7044697 at dilution 1:100)

Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded human rectum tissue using MBS7044697 at dilution 1:100)
Related Product Information for anti-CCP110 antibody
Necessary for centrosome duplication at different stages of procentriole formation. Acts as a key negative regulator of ciliogenesis in collaboration with CEP97 by capping the mother centriole thereby preventing cilia formation (PubMed:17719545 PubMed:17681131, PubMed:23486064). Also involved in promoting ciliogenesis. May play a role in the assembly of the mother centriole subdistal appendages (SDA) thereby effecting the fusion of recycling endosomes to basal bodies during cilia formation (By similarity). Required for correct spindle formation and has a role in regulating cytokinesis and genome stability via cooperation with CALM1 and CETN2 (PubMed:16760425).

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
111,224 Da
NCBI Official Full Name
centriolar coiled-coil protein of 110 kDa isoform 1
NCBI Official Synonym Full Names
centriolar coiled-coil protein 110
NCBI Official Symbol
CCP110
NCBI Official Synonym Symbols
CP110; Cep110
NCBI Protein Information
centriolar coiled-coil protein of 110 kDa
UniProt Protein Name
Centriolar coiled-coil protein of 110 kDa
UniProt Gene Name
CCP110
UniProt Synonym Gene Names
CEP110; CP110; KIAA0419; CP110; Cep110
UniProt Entry Name
CP110_HUMAN

Uniprot Description

CP110: Necessary for centrosome duplication at different stages of procentriole formation. Collaborates with CEP97, being involved in the suppression of a cilia assembly program. Required for correct spindle formation and has a role in regulating cytokinesis and genome stability via cooperation with CALM1 and CETN2. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Cell cycle regulation

Chromosomal Location of Human Ortholog: 16p12.3

Cellular Component: centriole; centrosome; cytosol; protein complex

Molecular Function: protein binding

Biological Process: basal body organization and biogenesis; centriole replication; centrosome duplication; G2/M transition of mitotic cell cycle; positive regulation of flagellum biogenesis; regulation of cytokinesis

Research Articles on CCP110

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Product Notes

The CCP110 ccp110 (Catalog #AAA7044697) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The CCP110 Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's CCP110 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC). Researchers should empirically determine the suitability of the CCP110 ccp110 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CCP110, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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