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Immunohistochemistry (Immunohistochemistry of paraffin-embedded human pancreas tissue slide using CCK Polyclonal Antibody at dilution of 1:200.)

Rabbit anti-Human CCK Polyclonal Antibody | anti-CCK antibody

CCK Antibody

Reactivity
Human
Applications
ELISA, Immunohistochemistry
Purity
Affinity purification
Synonyms
CCK; Polyclonal Antibody; CCK Antibody; CCK33 Cholecystokinin 25; CCK39 Cholecystokinin 33; CCK5; CCK7 Cholecystokinin 5; CCK8 Cholecystokinin 7; cholecystokinin; anti-CCK antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Affinity purification
Form/Format
PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Sequence Length
115
Applicable Applications for anti-CCK antibody
ELISA (EIA), Immunohistochemistry (IHC)
Application Notes
IHC; 1:50-1:500
Immunogen
Fusion protein of CCK
Santa Cruz Alternative
Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-21614 / sc-21617 / sc-20937
Note
Centrifuge before opening to ensure complete recovery of vial contents.
Preparation and Storage
Store at -20 degree C. Avoid freeze / thaw cycles

Immunohistochemistry

(Immunohistochemistry of paraffin-embedded human pancreas tissue slide using CCK Polyclonal Antibody at dilution of 1:200.)

Immunohistochemistry (Immunohistochemistry of paraffin-embedded human pancreas tissue slide using CCK Polyclonal Antibody at dilution of 1:200.)
Related Product Information for anti-CCK antibody
Cholecystokinin (CCK) is a classic gut hormone. CCK is also a complex system of peptides expressed in several molecular forms in enteroendocrine I cells, in cerebral and peripheral neurons, in cardiac myocytes and spermatozoa. The encoded preproprotein is proteolytically processed to generate multiple protein products, including the peptide hormones cholecystokinin-8, -12, -33, and others. The encoded peptides have been shown to regulate gastric acid secretion and food intake.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
885
UniProt Accession #
Molecular Weight
13kDa
NCBI Official Full Name
CCK, partial
NCBI Official Synonym Full Names
cholecystokinin
NCBI Official Symbol
CCK
NCBI Protein Information
cholecystokinin; cholecystokinin triacontatriapeptide; prepro-cholecystokinin
UniProt Protein Name
CCK protein
Protein Family
UniProt Gene Name
CCK
UniProt Entry Name
Q6FG82_HUMAN

NCBI Description

Cholecystokinin is a brain/gut peptide. In the gut, it induces the release of pancreatic enzymes and the contraction of the gallbladder. In the brain, its physiologic role is unclear. The cholecystokinin pro-hormone is processed by endo- and exo-proteolytic cleavages. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Mar 2010]

Uniprot Description

CCK: This peptide hormone induces gall bladder contraction and the release of pancreatic enzymes in the gut. Its function in the brain is not clear. Binding to CCK-A receptors stimulates amylase release from the pancreas, binding to CCK-B receptors stimulates gastric acid secretion. Belongs to the gastrin/cholecystokinin family.

Protein type: Hormone; Secreted, signal peptide; Secreted; Cell development/differentiation

Chromosomal Location of Human Ortholog: 3p22.1

Cellular Component: axon hillock; extracellular space; axon; dendrite; extracellular region; terminal button; perikaryon

Molecular Function: neuropeptide hormone activity; protein binding; hormone activity

Biological Process: caspase activation; positive regulation of protein oligomerization; positive regulation of peptidyl-tyrosine phosphorylation; release of cytochrome c from mitochondria; behavioral fear response; positive regulation of mitochondrial depolarization; axonogenesis; eating behavior; protein kinase C activation; positive regulation of cell proliferation; neuron migration; regulation of sensory perception of pain; signal transduction; negative regulation of appetite

Research Articles on CCK

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Product Notes

The CCK cck (Catalog #AAA2524352) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The CCK Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's CCK can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Immunohistochemistry (IHC). IHC; 1:50-1:500. Researchers should empirically determine the suitability of the CCK cck for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CCK, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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