Testing Data
(Figure-1: Expression analysis Cbx5. Anti-Cbx5 antibody (11-12009) was used at 2 ug/ml on (1) Jurkat, (2) MCF-7 and (3) EL-4 lysates.)
Rabbit anti-Mouse, Human Cbx5 Polyclonal Antibody | anti-CBX5 antibody
Polyclonal Antibody to Cbx5
Protein A Chromatography
Protein A Chromatography
For long-term storage, store at -20 degree C.
Avoid repeat freezing and thawing
Testing Data
(Figure-1: Expression analysis Cbx5. Anti-Cbx5 antibody (11-12009) was used at 2 ug/ml on (1) Jurkat, (2) MCF-7 and (3) EL-4 lysates.)
Testing Data
(Figure-1: Expression analysis Cbx5. Anti-Cbx5 antibody (11-12009) was used at 2 ug/ml on (1) Jurkat, (2) MCF-7 and (3) EL-4 lysates.)
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a highly conserved nonhistone protein, which is a member of the heterochromatin protein family. The protein is enriched in the heterochromatin and associated with centromeres. The protein has a single N-terminal chromodomain which can bind to histone proteins via methylated lysine residues, and a C-terminal chromo shadow-domain (CSD) which is responsible for the homodimerization and interaction with a number of chromatin-associated nonhistone proteins. The encoded product is involved in the formation of functional kinetochore through interaction with essential kinetochore proteins. The gene has a pseudogene located on chromosome 3. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Jul 2008]
Uniprot Description
Component of heterochromatin that recognizes and binds histone H3 tails methylated at 'Lys-9' (H3K9me), leading to epigenetic repression. In contrast, it is excluded from chromatin when 'Tyr-41' of histone H3 is phosphorylated (H3Y41ph). Can interact with lamin-B receptor (LBR). This interaction can contribute to the association of the heterochromatin with the inner nuclear membrane. Involved in the formation of functional kinetochore through interaction with MIS12 complex proteins.
Research Articles on CBX5
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Product Notes
The CBX5 cbx5 (Catalog #AAA669056) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Polyclonal Antibody to Cbx5 reacts with Mouse, Human and may cross-react with other species as described in the data sheet. AAA Biotech's Cbx5 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). WB analysis: 2-4 ug/ml. Researchers should empirically determine the suitability of the CBX5 cbx5 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Cbx5, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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