Rabbit anti-Human, Mouse CBLN2 Polyclonal Antibody | anti-CBLN2 antibody

CBLN2, CT (CBLN2, Cerebellin-2) (Azide free) (HRP)

Cat. Num. AAA6281138

• Reactivity: Human, Mouse
• Applications: Immunohistochemistry, ELISA, Western Blot
• Purity: Purified by Protein A Affinity Chromatography.
• Synonyms: CBLN2; Polyclonal Antibody; CT (CBLN2; Cerebellin-2) (Azide free) (HRP); Cerebellin-2; anti-CBLN2 antibody

• Host: Rabbit
• Reactivity: Human, Mouse
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: Purified by Protein A Affinity Chromatography.
• Form/Format: Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Horseradish Peroxidase (HRP).

• Applicable Applications for anti-CBLN2 antibody: Immunohistochemistry (IHC), ELISA (EIA), Western Blot (WB)
• Application Notes: IHC: 1:10-50; ELISA: 1:1,000; WB: 1:100-500; Applications are based on unconjugated antibody.
• Immunogen: CBLN2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 186-215 amino acids from the C-terminal region of human CBLN2.
• Conjugate: HRP
• Note: Preservative Free
• Preparation and Storage: Store product at 4 degree C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20 degree C. Aliquots are stable at -20 degree C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Note: Sodium azide is a potent inhibitor of peroxidase and should not be added to HRP conjugates. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Immunohistochemistry (IHC)

(CBLN2 Antibody (C-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human breast carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of CBLN2 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.)

Western Blot (WB)

(CBLN2 Antibody (C-term) western blot analysis in mouse brain tissue and MDA-MB231 cell line lysates (35ug/lane).This demonstrates the CBLN2 antibody detected the CBLN2 protein (arrow).)

Related Product Information for anti-CBLN2 antibody

CBLN2, Cerebellin 2, is a secreted glycoprotein and, like Cerebellin 1, may also serve as transneuronal regulators of synaptic functions in various brain regions.

Product Categories/Family for anti-CBLN2 antibody

Antibodies; Neuroscience

References

Grant, S.F., et al. J. Pediatr. 155(6):909-913(2009). Baranzini, S.E., et al. Hum. Mol. Genet. 18(4):767-778(2009). Clark, H.F., et al. Genome Res. 13(10):2265-2270(2003). Kavety, B., et al. Brain Res. Mol. Brain Res. 27(1):152-156(1994).

NCBI and Uniprot Product Information

• NCBI GI #: 32698861
• NCBI GeneID: 147381
• NCBI Accession #: NP_872317.1
• NCBI GenBank Nucleotide #: NM_182511.3
• UniProt Accession #: Q8IUK8; Q53Z56
• Molecular Weight: 24,084 Da
• NCBI Official Full Name: cerebellin-2
• NCBI Official Synonym Full Names: cerebellin 2 precursor
• NCBI Official Symbol: CBLN2
• NCBI Protein Information: cerebellin-2
• UniProt Protein Name: Cerebellin-2
• Protein Family: Cerebellin
• UniProt Gene Name: CBLN2
• UniProt Entry Name: CBLN2_HUMAN

Uniprot Description

CBLN2: May interact with CBLN1, CBLN3 and CBLN4.

Protein type: Membrane protein, integral

Chromosomal Location of Human Ortholog: 18q22.3

Cellular Component: extracellular space

Biological Process: positive regulation of synaptogenesis