Western Blot (WB)
(Western blot (WB) analysis of CBLN2 pAb at 1:500 dilutionLane1:C6 whole cell lysate(40ug)Lane2:PC3 whole cell lysate(40ug)Lane3:HCT116 whole cell lysate(40ug))
Rabbit anti-Human, Rat Cerebellin 2 Polyclonal Antibody | anti-CBLN2 antibody
Cerebellin 2 (L202) polyclonal antibody
Reactivity
Human, Rat
Applications
Western Blot
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. The purity is >95% (by SDS-PAGE).
Synonyms
Cerebellin 2; Polyclonal Antibody; Cerebellin 2 (L202) polyclonal antibody; CBLN2; UNQ1892/PRO4338; Cerebellin2; Cerebellin-2; anti-CBLN2 antibody
Host
Rabbit
Reactivity
Human, Rat
Clonality
Polyclonal
Isotype
Rabbit IgG
Specificity
Cerebellin 2 (L202) polyclonal antibody detects endogenous levels of Cerebellin 2 protein.
Purity/Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. The purity is >95% (by SDS-PAGE).
Form/Format
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Applicable Applications for anti-CBLN2 antibody
Western Blot (WB)
Application Notes
WB: 1:500~1:1000
Immunogen
Synthetic peptide, corresponding to amino acids 170-222 of Human Cerebellin 2.
Preparation and Storage
Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze-thaw cycles.
Western Blot (WB)
(Western blot (WB) analysis of CBLN2 pAb at 1:500 dilutionLane1:C6 whole cell lysate(40ug)Lane2:PC3 whole cell lysate(40ug)Lane3:HCT116 whole cell lysate(40ug))
Western Blot (WB)
(Western blot (WB) analysis of CBLN2 pAb at 1:500 dilutionLane1:C6 whole cell lysate(40ug)Lane2:PC3 whole cell lysate(40ug)Lane3:HCT116 whole cell lysate(40ug))
Related Product Information for anti-CBLN2 antibody
Cerebellin (CER), which was originally isolated from rat cerebellum, is a hexadecapeptide derived from a larger precursor called Cerebellin 1, also designated precerebellin 1 or Cbln1. Four propeptides, Cerebellin 1, Cerebellin 2 (Cbln2), Cerebellin 3 (Cbln3) and Cerebellin 4 (Cbln4), comprise the precerebellin subfamily within the C1q protein family. Cerebellin family members act as transneuronal regulators of synapse development and synaptic plasticity in various brain regions. Cerebellin and its metabolite, des-Ser(1)Cer, are also expressed in several extra-cerebellar tissues, including adrenal gland. Cerebellin 1, 2 and 3 assemble into homomeric and heteromeric complexes, thereby influencing each other’s degradation and secretion. Cerebellin 3 is not able to form homomeric complexes, and can only be secreted upon forming a heteromeric complex with Cerebellin 1. Decreased concentrations of Cerebellin have been found in the brain of patients with olivopontocerebellar atrophy (OPCA) and Shy-Drager syndrome, suggesting a role for Cerebellin in the pathology of these diseases.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
24,084 Da
NCBI Official Full Name
cerebellin-2
NCBI Official Synonym Full Names
cerebellin 2 precursor
NCBI Official Symbol
CBLN2
NCBI Protein Information
cerebellin-2
UniProt Protein Name
Cerebellin-2
Protein Family
UniProt Gene Name
CBLN2
UniProt Entry Name
CBLN2_HUMAN
Uniprot Description
CBLN2: May interact with CBLN1, CBLN3 and CBLN4.
Protein type: Membrane protein, integral
Chromosomal Location of Human Ortholog: 18q22.3
Cellular Component: extracellular space
Biological Process: positive regulation of synaptogenesis
Research Articles on CBLN2
Similar Products
Product Notes
The CBLN2 cbln2 (Catalog #AAA3014585) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Cerebellin 2 (L202) polyclonal antibody reacts with Human, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's Cerebellin 2 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). WB: 1:500~1:1000. Researchers should empirically determine the suitability of the CBLN2 cbln2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Cerebellin 2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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