Western Blot (WB)
(Western blot analysis of CATSPER1 using K562 whole cell lysates)
Rabbit anti-Human CATSPER1 Polyclonal Antibody | anti-CATSPER1 antibody
CATSPER1 Antibody
Gene Names
CATSPER1; SPGF7; CATSPER
Reactivity
Human
Applications
Western Blot, ELISA
Purity
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin.
Synonyms
CATSPER1; Polyclonal Antibody; CATSPER1 Antibody; Cation channel sperm associated 1; Cation channel sperm associated protein 1; Cation channel sperm-associated protein 1; CATSPER 1; CATSPER; CatSper1; CTSR1_HUMAN; hCatSper; MGC33335; MGC33368; Sperm associated cation channel 1; Sperm ion channel; anti-CATSPER1 antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Specificity
CATSPER1 antibody detects endogenous levels of total CATSPER1
Purity/Purification
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin.
Form/Format
Liquid
Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration
1mg/ml (varies by lot)
Sequence Length
780
Applicable Applications for anti-CATSPER1 antibody
Western Blot (WB), ELISA (EIA)
Application Notes
WB: 1:1000-3000
Immunogen
A synthesized peptide derived from human CATSPER1
Subcellular Location
Cell Projection > Cilium > Flagellum Membrane. Specifically located in the principal piece of sperm tail.
Tissue Specificity
Testis-specific.
Conjugation
Unconjugated
Preparation and Storage
Store at -20 degree C. Stable for 12 months from date of receipt.
Western Blot (WB)
(Western blot analysis of CATSPER1 using K562 whole cell lysates)
Western Blot (WB)
(Western blot analysis of CATSPER1 using K562 whole cell lysates)
Related Product Information for anti-CATSPER1 antibody
Function: Voltage-gated calcium channel that plays a central role in calcium-dependent physiological responses essential for successful fertilization, such as sperm hyperactivation, acrosome reaction and chemotaxis towards the oocyte.
Subunit Structure: Heterotetramer; possibly composed of CATSPER1, CATSPER2, CATSPER3 and CATSPER4 (Potential). Component of the CatSper complex. Interacts with CATSPER3 and CATSPER4 (By similarity). Interacts with Ca(v)3.3/CACNA1I, leading to suppress T-type calcium channel activity.
Similarity: Belongs to the cation channel sperm-associated (TC 1.A.1.19) family.
Subunit Structure: Heterotetramer; possibly composed of CATSPER1, CATSPER2, CATSPER3 and CATSPER4 (Potential). Component of the CatSper complex. Interacts with CATSPER3 and CATSPER4 (By similarity). Interacts with Ca(v)3.3/CACNA1I, leading to suppress T-type calcium channel activity.
Similarity: Belongs to the cation channel sperm-associated (TC 1.A.1.19) family.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
Observed: 90 kDa
Predicted: 91 kDa
Predicted: 91 kDa
NCBI Official Full Name
cation channel sperm-associated protein 1
NCBI Official Synonym Full Names
cation channel sperm associated 1
NCBI Official Symbol
CATSPER1
NCBI Official Synonym Symbols
SPGF7; CATSPER
NCBI Protein Information
cation channel sperm-associated protein 1
UniProt Protein Name
Cation channel sperm-associated protein 1
Protein Family
UniProt Gene Name
CATSPER1
UniProt Synonym Gene Names
CatSper1; hCatSper
NCBI Description
Calcium ions play a primary role in the regulation of sperm motility. This gene belongs to a family of putative cation channels that are specific to spermatozoa and localize to the flagellum. The protein family features a single repeat with six membrane-spanning segments and a predicted calcium-selective pore region. [provided by RefSeq, Jul 2008]
Uniprot Description
Voltage-gated calcium channel that plays a central role in calcium-dependent physiological responses essential for successful fertilization, such as sperm hyperactivation, acrosome reaction and chemotaxis towards the oocyte.
Research Articles on CATSPER1
Similar Products
Product Notes
The CATSPER1 catsper1 (Catalog #AAA9609666) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The CATSPER1 Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's CATSPER1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). WB: 1:1000-3000. Researchers should empirically determine the suitability of the CATSPER1 catsper1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CATSPER1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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