Rabbit anti-Human CAMP Polyclonal Antibody | anti-CAMP antibody

CAMP, CT (CAMP, CAP18, FALL39, Cathelicidin antimicrobial peptide, 18kD cationic antimicrobial protein, Antibacterial protein FALL-39, FALL-39 peptide antibiotic, Antibacterial protein LL-37) (MaxLight 750)

Cat. Num. AAA6280692

• Gene Names: CAMP; LL37; CAP18; CRAMP; HSD26; CAP-18; FALL39; FALL-39
• Reactivity: Human
• Applications: Western Blot
• Purity: Purified by Protein A and Peptide Affinity Chromatography.
• Synonyms: CAMP; Polyclonal Antibody; CT (CAMP; CAP18; FALL39; Cathelicidin antimicrobial peptide; 18kD cationic antimicrobial protein; Antibacterial protein FALL-39; FALL-39 peptide antibiotic; Antibacterial protein LL-37) (MaxLight 750); Antibacterial protein LL-37; anti-CAMP antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Isotype: IgG
• Specificity: Recognizes human CAMP.
• Purity/Purification: Purified by Protein A and Peptide Affinity Chromatography.
• Form/Format: Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with MaxLight750.

• Applicable Applications for anti-CAMP antibody: Western Blot (WB), FLISA
• Application Notes: Applications are based on unconjugated antibody.
• Immunogen: KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 123-152 in the C-terminal region of human CAMP.
• Conjugate: MaxLight750
• Note: Preservative Free
• Preparation and Storage: Store product at 4 degree C in the dark. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: MaxLight750 conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.

Western Blot (WB)

(Western Blot analysis in NCI-H292 cell line lysates (35ug/lane) using 033171. This demonstrates that 033171 detected the CAMP protein (arrow).)

Related Product Information for anti-CAMP antibody

Cathelicidin antimicrobial protein is an antimicrobial protein found in specific granules of polymorphonuclear leukocytes (PMNs).

Product Categories/Family for anti-CAMP antibody

Antibodies; Proteins

References

1. van der Does, A.M., et al. J. Immunol. 185(3):1442-1449(2010). 2. Jiang, Y., et al. Respirology 15(6):939-946(2010). 3. Goo, J., et al. Pediatr Dermatol 27(4):341-348(2010). 4. Kai-Larsen, Y., et al. PLoS Pathog. 6 (7), E1001010 (2010). 5. Pistolic, J., et al. J Innate Immun 1(3):254-267(2009).

NCBI and Uniprot Product Information

• NCBI GI #: 39753970
• NCBI GeneID: 820
• NCBI Accession #: NP_004336.2
• NCBI GenBank Nucleotide #: NM_004345.3
• UniProt Accession #: P49913; Q71SN9
• NCBI Official Full Name: cathelicidin antimicrobial peptide
• NCBI Official Synonym Full Names: cathelicidin antimicrobial peptide
• NCBI Official Symbol: CAMP
• NCBI Official Synonym Symbols: LL37; CAP18; CRAMP; HSD26; CAP-18; FALL39; FALL-39
• NCBI Protein Information: cathelicidin antimicrobial peptide; 18 kDa cationic antimicrobial protein
• UniProt Protein Name: Cathelicidin antimicrobial peptide
• Protein Family: CAMPATH-1 antigen
• UniProt Gene Name: CAMP
• UniProt Synonym Gene Names: CAP18; FALL39; CAP-18; hCAP-18
• UniProt Entry Name: CAMP_HUMAN

NCBI Description

This gene encodes a member of an antimicrobial peptide family, characterized by a highly conserved N-terminal signal peptide containing a cathelin domain and a structurally variable cationic antimicrobial peptide, which is produced by extracellular proteolysis from the C-terminus. In addition to its antibacterial, antifungal, and antiviral activities, the encoded protein functions in cell chemotaxis, immune mediator induction, and inflammatory response regulation. [provided by RefSeq, Sep 2014]

Uniprot Description

CAMP: Binds to bacterial lipopolysaccharides (LPS), has antibacterial activity. Belongs to the cathelicidin family.

Protein type: Secreted, signal peptide; Vesicle; Secreted; Cell cycle regulation

Chromosomal Location of Human Ortholog: 3p21.3

Cellular Component: extracellular space; specific granule; cell projection; cell wall; cytosol

Molecular Function: protein binding

Biological Process: interaction with host; defense response to Gram-positive bacterium; positive regulation of angiogenesis; innate immune response in mucosa; killing by host of symbiont cells; positive regulation of cell proliferation; defense response to bacterium; antibacterial humoral response; positive regulation of protein amino acid phosphorylation; defense response to Gram-negative bacterium