Western Blot (WB)
Rabbit anti-Human Caspase 4 Polyclonal Antibody | anti-Casp4 antibody
Anti-Caspase 4 Antibody
Gene Names
Casp4; Casp11
Reactivity
Human
Applications
ELISA, Western Blot
Purity
Protein A purified
Synonyms
Caspase 4; Polyclonal Antibody; Anti-Caspase 4 Antibody; anti-Casp4 antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Specificity
Caspase 4 antibody detects endogenous levels of Caspase 4 protein. Not tested with other proteins
Purity/Purification
Protein A purified
Form/Format
Liquid
Concentration
100ug/100ul (varies by lot)
Sequence Length
373
Applicable Applications for anti-Casp4 antibody
Peptide ELISA (EIA), Western Blot (WB)
Application Notes
Recommended dilutions:
Peptide ELISA: 1:20,000
WB: 1:100 - 1:500
Not yet tested in other applications. Optimal dilutions/concentrations should be determined by the end user.
Peptide ELISA: 1:20,000
WB: 1:100 - 1:500
Not yet tested in other applications. Optimal dilutions/concentrations should be determined by the end user.
Storage Buffer
PBS, pH 7.4 with 0.02% Sodium Azide
Immunogen
Synthetic peptide conjugated to KLH
Preparation and Storage
This product is stable for several weeks at 4 degree C as an undiluted liquid. Dilute only prior to immediate use. For extended storage, aliquot contents and freeze at -20 degree C or below. Avoid cycles of freezing and thawing. Expiration date is one (1) year from date of receipt.
Western Blot (WB)
Western Blot (WB)
Related Product Information for anti-Casp4 antibody
This gene encodes a protein that is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes composed of a prodomain and a large and small protease subunit. Activation of caspases requires proteolytic processing at conserved internal aspartic residues to generate a heterodimeric enzyme consisting of the large and small subunits. This caspase is able to cleave and activate its own precursor protein, as well as caspase 1 precursor. When overexpressed, this gene induces cell apoptosis. Alternative splicing results in transcript variants encoding distinct isoforms.
References
Howard,A.D.,Kostura,M.J.,Thornberry,N.et,al IL-1-converting enzyme requires aspartic acid residues for processing of the IL-1 beta precursor at two distinct sites and does not cleave 31-kDa IL-1 alpha
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
NCBI Official Full Name
caspase 4
NCBI Official Synonym Full Names
caspase 4, apoptosis-related cysteine peptidase
NCBI Official Symbol
Casp4
NCBI Official Synonym Symbols
Casp11
NCBI Protein Information
caspase 4; caspase 11
Protein Family
NCBI Description
cysteine-aspartic acid protease (caspase); involved with the terminal stage of apoptosis; may also be involved with response to inflammation [RGD, Feb 2006]
Research Articles on Casp4
Similar Products
Product Notes
The Casp4 (Catalog #AAA416822) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-Caspase 4 Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's Caspase 4 can be used in a range of immunoassay formats including, but not limited to, Peptide ELISA (EIA), Western Blot (WB). Recommended dilutions: Peptide ELISA: 1:20,000 WB: 1:100 - 1:500 Not yet tested in other applications. Optimal dilutions/concentrations should be determined by the end user. Researchers should empirically determine the suitability of the Casp4 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Caspase 4, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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