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Immunohistochemistry (IHC) (Anti-CASC4 antibody IHC staining of human prostate. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.)

Rabbit anti-Mouse, Human CASC4 Polyclonal Antibody | anti-CASC4 antibody

Anti-CASC4 Antibody (aa343-373) IHC-plus

Gene Names
CASC4; H63
Reactivity
Mouse, Human
Applications
Immunohistochemistry, Western Blot, Flow Cytometry, Functional Assay
Purity
Immunoaffinity purified
Synonyms
CASC4; Polyclonal Antibody; Anti-CASC4 Antibody (aa343-373) IHC-plus; Rabbit Polyclonal to Human CASC4; Human CASC4; H63; Protein CASC4; anti-CASC4 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Mouse, Human
Clonality
Polyclonal
Specificity
Human CASC4
Purity/Purification
Immunoaffinity purified
Form/Format
PBS, 0.09% sodium azide
Sequence Length
467
Applicable Applications for anti-CASC4 antibody
Immunohistochemistry (IHC) Paraffin, Western Blot (WB), Flow Cytometry (FC/FACS)
Application Notes
Flow Cytometry (1:10 - 1:50)
IHC-P (1:100)
WB (1:1000)
Immunogen
CASC4 antibody was raised against kLH-conjugated synthetic peptide from C-terminal region of human CASC4.
Immunogen Description
KLH-conjugated synthetic peptide from C-terminal region of human CASC4.
Immunogen Type
Synthetic peptide
Antigen Modification
aa343-373
Target Species
Human
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months.
For long term storage store at -20 degree C.

Immunohistochemistry (IHC)

(Anti-CASC4 antibody IHC staining of human prostate. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.)

Immunohistochemistry (IHC) (Anti-CASC4 antibody IHC staining of human prostate. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.)

Immunohistochemistry (IHC)

(Anti-CASC4 antibody IHC staining of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:100.)

Immunohistochemistry (IHC) (Anti-CASC4 antibody IHC staining of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:100.)

Western Blot (WB)

(CASC4 Antibody western blot of mouse Neuro-2a cell line lysates (35 ug/lane). The CASC4 antibody detected the CASC4 protein (arrow).)

Western Blot (WB) (CASC4 Antibody western blot of mouse Neuro-2a cell line lysates (35 ug/lane). The CASC4 antibody detected the CASC4 protein (arrow).)

Flow Cytometry (FC/FACS)

(CASC4 Antibody flow cytometry of Neuro-2a cells (right histogram) compared to a negative control cell (left histogram). FITC-conjugated donkey-anti-rabbit secondary antibodies were used for the analysis.)

Flow Cytometry (FC/FACS) (CASC4 Antibody flow cytometry of Neuro-2a cells (right histogram) compared to a negative control cell (left histogram). FITC-conjugated donkey-anti-rabbit secondary antibodies were used for the analysis.)
Related Product Information for anti-CASC4 antibody
CASC4 Antibody, H63 Antibody, Protein CASC4 Antibody Description: The increased expression level of this gene is associated with HER-2/neu proto-oncogene overexpression. Amplification and resulting overexpression of this proto-oncogene are found in approximately 30% of human breast and 20% of human ovarian cancers. Alternatively spliced variants encoding different isoforms have been identified for this gene.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
Molecular Weight
47,308 Da
NCBI Official Full Name
CASC4
NCBI Official Synonym Full Names
cancer susceptibility candidate 4
NCBI Official Symbol
CASC4
NCBI Official Synonym Symbols
H63
NCBI Protein Information
protein CASC4
UniProt Protein Name
Protein CASC4
Protein Family
UniProt Gene Name
CASC4
UniProt Entry Name
CASC4_HUMAN

NCBI Description

The increased expression level of this gene is associated with HER-2/neu proto-oncogene overexpression. Amplification and resulting overexpression of this proto-oncogene are found in approximately 30% of human breast and 20% of human ovarian cancers. Alternatively spliced variants encoding different isoforms have been identified for this gene. [provided by RefSeq, Dec 2010]

Uniprot Description

CASC4: The increased expression level of this gene is associated with HER-2/neu proto-oncogene overexpression. Amplification and resulting overexpression of this proto-oncogene are found in approximately 30% of human breast and 20% of human ovarian cancers. Alternatively spliced variants encoding different isoforms have been identified for this gene. [provided by RefSeq, Dec 2010]

Protein type: Membrane protein, integral

Chromosomal Location of Human Ortholog: 15q15.3

Cellular Component: Golgi apparatus; integral to membrane

Research Articles on CASC4

Similar Products

Product Notes

The CASC4 casc4 (Catalog #AAA2400470) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-CASC4 Antibody (aa343-373) IHC-plus reacts with Mouse, Human and may cross-react with other species as described in the data sheet. AAA Biotech's CASC4 can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC) Paraffin, Western Blot (WB), Flow Cytometry (FC/FACS). Flow Cytometry (1:10 - 1:50) IHC-P (1:100) WB (1:1000). Researchers should empirically determine the suitability of the CASC4 casc4 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CASC4, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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