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Sheep anti-Human Carbonic Anhydrase III Polyclonal Antibody | anti-CA3 antibody

Carbonic Anhydrase III (CAIII)

Gene Names
CA3; Car3; CAIII; FLJ36434
Reactivity
Human
Applications
ELISA
Purity
Purified
Purified
Synonyms
Carbonic Anhydrase III; Polyclonal Antibody; Carbonic Anhydrase III (CAIII); Anti -Carbonic Anhydrase III (CAIII); anti-CA3 antibody
Ordering
For Research Use Only!
Host
Sheep
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Specificity
Recognizes human CAIII.
Purity/Purification
Purified
Purified
Form/Format
Supplied as a liquid in 20mM phosphate, 150mM sodium chloride, pH 7.2, 0.09% sodium azide.
Applicable Applications for anti-CA3 antibody
ELISA (EL/EIA)
Application Notes
Suitable for use in ELISA.
Immunogen
Recombinant corresponding to human CAIII, fused to 6x His-tag at N-terminal, expressed in E. coli.
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Related Product Information for anti-CA3 antibody
Carbonic anhydrase III is one of a group of ten zinc metalloenzymes that catalyse the reversible hydration of CO2 to form HCO3. CAIII is a cytoplasmic isoenzyme, but is released into the circulation following injury.
Product Categories/Family for anti-CA3 antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
761
UniProt Accession #
Molecular Weight
29,557 Da
NCBI Official Full Name
carbonic anhydrase III
NCBI Official Synonym Full Names
carbonic anhydrase III, muscle specific
NCBI Official Symbol
CA3
NCBI Official Synonym Symbols
Car3; CAIII; FLJ36434
NCBI Protein Information
carbonic anhydrase 3; CA-III; OTTHUMP00000227990; carbonate dehydratase III
UniProt Protein Name
Carbonic anhydrase 3
Protein Family
UniProt Gene Name
CA3
UniProt Entry Name
CAH3_HUMAN

NCBI Description

Carbonic anhydrase III (CAIII) is a member of a multigene family (at least six separate genes are known) that encodes carbonic anhydrase isozymes. These carbonic anhydrases are a class of metalloenzymes that catalyze the reversible hydration of carbon dioxide and are differentially expressed in a number of cell types. The expression of the CA3 gene is strictly tissue specific and present at high levels in skeletal muscle and much lower levels in cardiac and smooth muscle. A proportion of carriers of Duchenne muscle dystrophy have a higher CA3 level than normal. The gene spans 10.3 kb and contains seven exons and six introns. [provided by RefSeq]

Uniprot Description

CA3: Reversible hydration of carbon dioxide. Belongs to the alpha-carbonic anhydrase family.

Protein type: Energy Metabolism - nitrogen; EC 4.2.1.1; Lyase

Chromosomal Location of Human Ortholog: 8q21.2

Cellular Component: cytosol

Molecular Function: carbonate dehydratase activity; zinc ion binding; nickel ion binding

Biological Process: response to ethanol; bicarbonate transport; response to oxidative stress; one-carbon compound metabolic process

Research Articles on CA3

Similar Products

Product Notes

The CA3 ca3 (Catalog #AAA622392) is an Antibody produced from Sheep and is intended for research purposes only. The product is available for immediate purchase. The Carbonic Anhydrase III (CAIII) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's Carbonic Anhydrase III can be used in a range of immunoassay formats including, but not limited to, ELISA (EL/EIA). Suitable for use in ELISA. Researchers should empirically determine the suitability of the CA3 ca3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Carbonic Anhydrase III, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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