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Testing Data (The OmniKine Human Total MMP-8 ELISA Kit allows for the detection and quantification of endogenous levels of natural and/or recombinant Human Total MMP-8 proteins within the range of 63-4000 pg/ml.)

Human Total MMP-8 ELISA Kit | MMP-8 elisa kit

Total MMP-8 (Human) OmniKine ELISA Kit

Gene Names
MMP8; HNC; CLG1; MMP-8; PMNL-CL
Reactivity
Human
Synonyms
Total MMP-8; Total MMP-8 (Human) OmniKine ELISA Kit; Neutrophil collagenase; Matrix metalloproteinase-8; PMNL collagenase; CLG1; MMP-8 elisa kit
Ordering
For Research Use Only!
Reactivity
Human
Specificity
The OmniKine Human MMP-8 ELISA is capable of recognizing both recombinant and naturally produced Human MMP-8 proteins. The antigens listed below were tested at 50 ng/ml and did not exhibit significant cross reactivity or interference.
Human: MMP-1, MMP-2, MMP-3, MMP-7, MMP-9, MMP-10, MMP-12, MMP-13, TIMP-1, TIMP-2
Form/Format
12 x 8-Well Microstrips
Sequence Length
444
Samples
Plasma, serum, lysate
Assay Type
Sandwich ELISA
Detection Range
63-4000 pg/ml
Sensitivity
63-4000 pg/ml
Detection Method
Colorimetric 450 nm
Subtype
None
Preparation and Storage
Store at 4 degree C for 6 months.

Testing Data

(The OmniKine Human Total MMP-8 ELISA Kit allows for the detection and quantification of endogenous levels of natural and/or recombinant Human Total MMP-8 proteins within the range of 63-4000 pg/ml.)

Testing Data (The OmniKine Human Total MMP-8 ELISA Kit allows for the detection and quantification of endogenous levels of natural and/or recombinant Human Total MMP-8 proteins within the range of 63-4000 pg/ml.)

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
53,412 Da
NCBI Official Full Name
neutrophil collagenase isoform 2
NCBI Official Synonym Full Names
matrix metallopeptidase 8
NCBI Official Symbol
MMP8
NCBI Official Synonym Symbols
HNC; CLG1; MMP-8; PMNL-CL
NCBI Protein Information
neutrophil collagenase
UniProt Protein Name
Neutrophil collagenase
UniProt Gene Name
MMP8
UniProt Synonym Gene Names
CLG1; MMP-8; PMNL-CL

NCBI Description

This gene encodes a member of the matrix metalloproteinase (MMP) family of proteins. These proteins are involved in the breakdown of extracellular matrix in embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Proteolysis at different sites on this protein results in multiple active forms of the enzyme with distinct N-termini. This protein functions in the degradation of type I, II and III collagens. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2015]

Uniprot Description

MMP8: Can degrade fibrillar type I, II, and III collagens. Belongs to the peptidase M10A family.

Protein type: EC 3.4.24.34; Protease; Secreted; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 11q22.2

Cellular Component: extracellular region; extracellular space; proteinaceous extracellular matrix

Molecular Function: metalloendopeptidase activity; serine-type endopeptidase activity; zinc ion binding

Biological Process: collagen catabolic process; extracellular matrix disassembly; neutrophil degranulation; proteolysis

Research Articles on MMP-8

Similar Products

Product Notes

The Human MMP-8 mmp8 (Catalog #AAA9502000) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9502000 ELISA Kit recognizes Human MMP-8. It is sometimes possible for the material contained within the vial of "Total MMP-8, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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