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Western Blot (WB) (Western blot analysis of extracts of various cell lines, using CAPN3 Antibody.)

Rabbit CAPN3 Polyclonal Antibody | anti-CAPN3 antibody

CAPN3 Polyclonal Antibody

Gene Names
CAPN3; p94; CANP3; LGMD2; nCL-1; CANPL3; LGMD2A; LGMDD4; LGMDR1
Reactivity
Human, Mouse, Rat
Applications
Western Blot
Purity
Affinity Purification
Synonyms
CAPN3; Polyclonal Antibody; CAPN3 Polyclonal Antibody; Calcium-activated neutral proteinase 3; calpain 3; (p94); Calpain L3; Calpain large polypeptide L3; Calpain p94; calpain p94; large [catalytic] subunit; calpain; large polypeptide L3; Calpain-3; CAN3; CANP 3; CANP3; CANPL3; LGMD 2A; LGMD2; LGMD2A; Lp82; Lp85; MGC10767; MGC11121; MGC14344; MGC4403; Muscle-specific calcium-activated neutral protease 3; muscle-specific calcium-activated neutral protease 3 large subunit; nCL-1; New calpain 1; p94; anti-CAPN3 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Affinity Purification
Form/Format
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Concentration
1 mg/mL (varies by lot)
Sequence Length
729
Applicable Applications for anti-CAPN3 antibody
Western Blot (WB)
Application Notes
WB: 1:500-1:2000
Immunogen
Recombinant protein of human CAPN3
Conjugation
Unconjugated
Preparation and Storage
Store at -20 degree C. Avoid freeze/thaw cycles.

Western Blot (WB)

(Western blot analysis of extracts of various cell lines, using CAPN3 Antibody.)

Western Blot (WB) (Western blot analysis of extracts of various cell lines, using CAPN3 Antibody.)
Related Product Information for anti-CAPN3 antibody
Calpain, a heterodimer consisting of a large and a small subunit, is a major intracellular protease, although its function has not been well established. This gene encodes a muscle-specific member of the calpain large subunit family that specifically binds to titin. Mutations in this gene are associated with limb-girdle muscular dystrophies type 2A. Alternate promoters and alternative splicing result in multiple transcript variants encoding different isoforms and some variants are ubiquitously expressed.
Product Categories/Family for anti-CAPN3 antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
825
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
Calculated: 18kDa; 35kDa; 84kDa; 93kDa; 94kDa
Observed: 114kDa
NCBI Official Full Name
calpain-3 isoform a
NCBI Official Synonym Full Names
calpain 3
NCBI Official Symbol
CAPN3
NCBI Official Synonym Symbols
p94; CANP3; LGMD2; nCL-1; CANPL3; LGMD2A; LGMDD4; LGMDR1
NCBI Protein Information
calpain-3
UniProt Protein Name
Calpain-3
Protein Family
UniProt Gene Name
CAPN3
UniProt Synonym Gene Names
CANP3; CANPL3; NCL1; CANP 3; nCL-1

NCBI Description

Calpain, a heterodimer consisting of a large and a small subunit, is a major intracellular protease, although its function has not been well established. This gene encodes a muscle-specific member of the calpain large subunit family that specifically binds to titin. Mutations in this gene are associated with limb-girdle muscular dystrophies type 2A. Alternate promoters and alternative splicing result in multiple transcript variants encoding different isoforms and some variants are ubiquitously expressed. [provided by RefSeq, Jul 2008]

Uniprot Description

Calcium-regulated non-lysosomal thiol-protease.

Research Articles on CAPN3

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Product Notes

The CAPN3 capn3 (Catalog #AAA2554493) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The CAPN3 Polyclonal Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's CAPN3 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). WB: 1:500-1:2000. Researchers should empirically determine the suitability of the CAPN3 capn3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CAPN3, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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