Western Blot (WB)
(Western Blot analysis of extracts of various cells, using CALHM1 antibody.)
Rabbit anti-Human, Rat CALHM1 Polyclonal Antibody | anti-CALHM1 antibody
CALHM1 Polyclonal Antibody
IHC: 1:50-1:200
Aliquot and store at -20 degree C long term.
Avoid freeze-thaw cycles.
Western Blot (WB)
(Western Blot analysis of extracts of various cells, using CALHM1 antibody.)
Western Blot (WB)
(Western Blot analysis of extracts of various cells, using CALHM1 antibody.)
Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded rat brain using CALHM1 antibody at dilution of 1:100 (x40 lens).)
Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded rat brain using CALHM1 antibody at dilution of 1:100 (x40 lens).)
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a calcium channel that plays a role in processing of amyloid-beta precursor protein. A polymorphism at this locus has been reported to be associated with susceptibility to late-onset Alzheimer's disease in some populations, but the pathogenicity of this polymorphism is unclear.[provided by RefSeq, Mar 2010]
Uniprot Description
CALHM1: May be a pore-forming ion channel. Controls cytosolic Ca(2+) permeability and cytosolic Ca(2+) concentration. Controls amyloid precursor protein (APP) proteolysis and aggregated amyloid-beta (Abeta) peptides levels in a Ca(2+) dependent manner. Belongs to the FAM26 family.
Protein type: Membrane protein, multi-pass; Membrane protein, integral; Channel, calcium
Chromosomal Location of Human Ortholog: 10q24.33
Cellular Component: endoplasmic reticulum membrane; integral to plasma membrane
Molecular Function: identical protein binding; calcium channel activity; voltage-gated ion channel activity; calcium activated cation channel activity
Biological Process: ATP transport; sensory perception of umami taste; sensory perception of sweet taste; sensory perception of bitter taste; cation transport; protein homooligomerization
Research Articles on CALHM1
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Product Notes
The CALHM1 calhm1 (Catalog #AAA3008919) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The CALHM1 Polyclonal Antibody reacts with Human, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's CALHM1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC). WB: 1:500-1:2000 IHC: 1:50-1:200. Researchers should empirically determine the suitability of the CALHM1 calhm1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CALHM1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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