Western Blot (WB)
(Western Blot: Sample: Rat Brain Tissue.)
Rabbit anti-Rat Calcium/Calmodulin Dependent Protein Kinase II Alpha Polyclonal Antibody | anti-CAMK2a antibody
Polyclonal Antibody to Calcium/Calmodulin Dependent Protein Kinase II Alpha (CAMK2a)
Immunohistochemistry: 5-20ug/mL
Immunocytochemistry: 5-20ug/mL
Optimal working dilutions must be determined by end user.
Western Blot (WB)
(Western Blot: Sample: Rat Brain Tissue.)
Western Blot (WB)
(Western Blot: Sample: Rat Brain Tissue.)
Western Blot (WB)
(Western Blot: Sample: Recombinant CAMK2a, Rat.)
Western Blot (WB)
(Western Blot: Sample: Recombinant CAMK2a, Rat.)
Immunohistochemistry (IHC)
(DAB staining on IHC-P; Samples: Rat Heart Tissue.)
Immunohistochemistry (IHC)
(DAB staining on IHC-P; Samples: Rat Heart Tissue.)
Immunohistochemistry (IHC)
(DAB staining on IHC-P; Samples: Rat Spinal Cord Tissue)
Immunohistochemistry (IHC)
(DAB staining on IHC-P; Samples: Rat Spinal Cord Tissue)
Immunohistochemistry (IHC)
(DAB staining on IHC-P; Samples: Rat Stomach Tissue)
Immunohistochemistry (IHC)
(DAB staining on IHC-P; Samples: Rat Stomach Tissue)
NCBI and Uniprot Product Information
Uniprot Description
CAMK2A: a protein kinase of the CAMK2 family. A prominent kinase in the central nervous system that may function in long-term potentiation and neurotransmitter release. Member of the NMDAR signaling complex in excitatory synapses that may regulate NMDAR-dependent potentiation of the AMPAR and synaptic plasticity. The holoenzyme is composed of four different chains: alpha, beta, gamma, and delta. The different chains assemble into homo- or heteromultimeric holoenzymes composed of 8 to 12 subunits. May interact with BAALC, MPDZ, SYN1 and synGAP. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: CAMK group; CAMK2 family; EC 2.7.11.17; Kinase, protein; Protein kinase, CAMK; Protein kinase, Ser/Thr (non-receptor)
Chromosomal Location of Human Ortholog: 18q12.1
Cellular Component: axon; cell junction; cell soma; dendrite; dendrite cytoplasm; mitochondrion; nucleus; postsynaptic density; presynaptic membrane
Molecular Function: ATP binding; calcium-dependent protein serine/threonine kinase activity; calmodulin binding; calmodulin-dependent protein kinase activity; glutamate receptor binding; GTPase activating protein binding; identical protein binding; kinase activity; metal ion binding; protein binding; protein homodimerization activity; protein serine/threonine kinase activity
Biological Process: angiotensin-activated signaling pathway; calcium ion transport; calmodulin dependent kinase signaling pathway; cell differentiation; dendrite morphogenesis; G1/S transition of mitotic cell cycle; ionotropic glutamate receptor signaling pathway; nervous system development; NMDA selective glutamate receptor signaling pathway; peptidyl-serine phosphorylation; peptidyl-threonine phosphorylation; positive regulation of calcium ion transport; positive regulation of cardiac muscle cell apoptotic process; positive regulation of NF-kappaB transcription factor activity; postsynaptic neurotransmitter receptor diffusion trapping; protein amino acid phosphorylation; protein autophosphorylation; regulation of mitochondrial membrane permeability involved in apoptotic process; regulation of neuronal synaptic plasticity; regulation of neurotransmitter secretion
Research Articles on CAMK2a
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Product Notes
The CAMK2a camk2a (Catalog #AAA2026315) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Polyclonal Antibody to Calcium/Calmodulin Dependent Protein Kinase II Alpha (CAMK2a) reacts with Rat and may cross-react with other species as described in the data sheet. AAA Biotech's Calcium/Calmodulin Dependent Protein Kinase II Alpha can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunocytochemistry (ICC), Immunohistochemistry (IHC) Formalin/Paraffin, ELISA (EIA). Western blotting: 0.5-2ug/mL Immunohistochemistry: 5-20ug/mL Immunocytochemistry: 5-20ug/mL Optimal working dilutions must be determined by end user. Researchers should empirically determine the suitability of the CAMK2a camk2a for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Calcium/Calmodulin Dependent Protein Kinase II Alpha, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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