Rabbit Calcitonin Receptor Polyclonal Antibody | anti-CTR antibody
Calcitonin Receptor (CTR) Polyclonal Antibody
Immunohistochemistry: 5-20ug/mL
Immunocytochemistry: 5-20ug/mL
Optimal working dilutions must be determined by end user.
Avoid repeated freeze/thaw cycles.
Store at 4 degree C for frequent use.
Aliquot and store at -20 degree C for 24 months.
Stability Test:
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 degree C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
Western Blot (WB)
(Western Blot;Sample: Mouse KidneyPrimary Ab: 1ug/ml Rabbit Anti-Mouse CTR AntibodySecond Ab: 0.2ug/mL HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody (Catalog: MBS2086047))
Immunohistochemistry (IHC)
(DAB staining on IHC-P;Samples: Mouse Kidney Tissue;Primary Ab: 20ug/ml Rabbit Anti-Mouse CTR AntibodySecond Ab: 2ug/mL HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody (Catalog: MBS2086047))
NCBI and Uniprot Product Information
Uniprot Description
CALCR: This is a receptor for calcitonin. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. The calcitonin receptor is thought to couple to the heterotrimeric guanosine triphosphate-binding protein that is sensitive to cholera toxin. Belongs to the G-protein coupled receptor 2 family. 3 isoforms of the human protein are produced by alternative splicing.
Protein type: GPCR, family 2; Membrane protein, integral; Membrane protein, multi-pass; Receptor, GPCR
Chromosomal Location of Human Ortholog: 6 A1|6 1.81 cM
Cellular Component: acrosomal vesicle; axon; cell; cell soma; cilium; integral component of membrane; membrane; neuron projection; plasma membrane
Molecular Function: calcitonin binding; calcitonin receptor activity; G-protein coupled receptor activity; protein transporter activity; receptor activity; signal transducer activity; transmembrane receptor activity
Biological Process: adenylate cyclase-activating G-protein coupled receptor signaling pathway; cell surface receptor signaling pathway; elevation of cytosolic calcium ion concentration; G-protein coupled receptor signaling pathway; G-protein signaling, coupled to cAMP nucleotide second messenger; negative regulation of ossification; osteoclast differentiation; positive regulation of adenylate cyclase activity; positive regulation of calcium ion import across plasma membrane; positive regulation of cAMP biosynthetic process; positive regulation of cAMP metabolic process; positive regulation of cell death; positive regulation of ERK1 and ERK2 cascade; positive regulation of gene expression; positive regulation of peptidyl-serine phosphorylation; positive regulation of protein kinase A signaling; positive regulation of protein kinase B signaling; protein localization to plasma membrane; protein transport; receptor internalization; regulation of bone resorption; regulation of mRNA stability; response to glucocorticoid stimulus; signal transduction
Research Articles on CTR
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Product Notes
The CTR calcr (Catalog #AAA2032223) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Calcitonin Receptor (CTR) Polyclonal Antibody reacts with Mus musculus (Mouse) and may cross-react with other species as described in the data sheet. AAA Biotech's Calcitonin Receptor can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB); Immunohistochemistry (IHC); Immunocytochemistry (ICC); Immunoprecipitation (IP). Western blotting: 0.5-2ug/mL Immunohistochemistry: 5-20ug/mL Immunocytochemistry: 5-20ug/mL Optimal working dilutions must be determined by end user. Researchers should empirically determine the suitability of the CTR calcr for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Calcitonin Receptor, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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