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Rabbit CAC1S Polyclonal Antibody | anti-CAC1S antibody

CAC1S Polyclonal Antibody

Gene Names
CACNA1S; MHS5; HOKPP; TTPP1; Cav1.1; HOKPP1; hypoPP; CCHL1A3; CACNL1A3
Reactivity
Human, Mouse, Rat
Applications
Western Blot, ELISA
Purity
Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Synonyms
CAC1S; Polyclonal Antibody; CAC1S Polyclonal Antibody; Voltage-dependent L-type calcium channel subunit alpha-1S; Calcium channel; L type; alpha-1 polypeptide; isoform 3; skeletal muscle; Voltage-gated calcium channel subunit alpha Cav1.1; CACNA1S; CACH1; CACN1; CACNL1A3; anti-CAC1S antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Purity/Purification
Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Form/Format
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Sequence Length
1873
Applicable Applications for anti-CAC1S antibody
Western Blot (WB), ELISA (EIA)
Application Notes
WB: 1:500-2000
ELISA: 1:5000-20000
Immunogen
Synthesized peptide derived from human protein. at AA range: 330-410
Preparation and Storage
Store at-20 degree C for 1 year.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
779
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
206
NCBI Official Full Name
voltage-dependent L-type calcium channel subunit alpha-1S
NCBI Official Synonym Full Names
calcium voltage-gated channel subunit alpha1 S
NCBI Official Symbol
CACNA1S
NCBI Official Synonym Symbols
MHS5; HOKPP; TTPP1; Cav1.1; HOKPP1; hypoPP; CCHL1A3; CACNL1A3
NCBI Protein Information
voltage-dependent L-type calcium channel subunit alpha-1S
UniProt Protein Name
Voltage-dependent L-type calcium channel subunit alpha-1S
UniProt Gene Name
CACNA1S

NCBI Description

This gene encodes one of the five subunits of the slowly inactivating L-type voltage-dependent calcium channel in skeletal muscle cells. Mutations in this gene have been associated with hypokalemic periodic paralysis, thyrotoxic periodic paralysis and malignant hyperthermia susceptibility. [provided by RefSeq, Jul 2008]

Uniprot Description

Pore-forming, alpha-1S subunit of the voltage-gated calcium channel that gives rise to L-type calcium currents in skeletal muscle. Calcium channels containing the alpha-1S subunit play an important role in excitation-contraction coupling in skeletal muscle via their interaction with RYR1, which triggers Ca2+ release from the sarcplasmic reticulum and ultimately results in muscle contraction. Long-lasting (L-type) calcium channels belong to the 'high-voltage activated' (HVA) group.

Research Articles on CAC1S

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Product Notes

The CAC1S cacna1s (Catalog #AAA8530880) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The CAC1S Polyclonal Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's CAC1S can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). WB: 1:500-2000 ELISA: 1:5000-20000. Researchers should empirically determine the suitability of the CAC1S cacna1s for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CAC1S, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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