Rabbit C1QL1 Polyclonal Antibody | anti-C1QL1 antibody

C1QL1 Polyclonal Antibody

Cat. Num. AAA3015200

• Gene Names: C1QL1; CRF; C1QRF; C1QTNF14
• Reactivity: Human, Mouse, Rat, Dog, Pig, Cow
• Applications: Immunohistochemistry
• Purity: affinity purified by Protein A
• Synonyms: C1QL1; Polyclonal Antibody; C1QL1 Polyclonal Antibody; C1q related factor; C1q-related factor; C1ql1; C1QRF; C1QRF_HUMAN; C1QTNF14; Complement component 1 Q subcomponent like 1; Complement component 1 Q subcomponent-like 1; CRF; Gliacolin; anti-C1QL1 antibody

• Host: Rabbit
• Reactivity: Human, Mouse, Rat, Dog, Pig, Cow
• Clonality: Polyclonal
• Specificity: C1QL1 Polyclonal Antibody detects endogenous levels of C1QL1 protein.
• Purity/Purification: affinity purified by Protein A
• Form/Format: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

• Applicable Applications for anti-C1QL1 antibody: Immunohistochemistry-Paraffin (IHC-P)
• Application Notes: IHC-P: 1:100-500
• Immunogen: KLH conjugated synthetic peptide derived from human C1QL1
• Preparation and Storage: Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze-thaw cycles.

Immunohistochemistry (IHC)

(Paraformaldehyde-fixed, paraffin embedded (rat brain); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (C1QL1) Polyclonal Antibody, Unconjugated at 1:200 overnight at 4°C)

Related Product Information for anti-C1QL1 antibody

C1q is part of the C1 enzyme complex, which activates the serum complement system. The residues of the globular domain in C1q share homology with several other secreted and membrane-bound collagen or collagen-like proteins, including pre-cerebellin and collagen types VIII and X, as well as the human and mouse genes encoding Apm1/BPB80 and AdipoQ/ACRP30, respectively. These various C1q-related proteins are found in adipose serum, corneal endothelium, chondrocytes and cerebral Purkinje cells. C1qL1 (complement component 1, q subcomponent-like 1), also known as CRF or C1QRF, is a polypeptide with a hydrophobic signal sequence, a collagenous region and a globular domain at the carboxy terminus, which shares homology to the C1q globular domain. C1qL1 transcripts are most abundant in areas of the nervous system that are associated with motor function, including cerebral Purkinje cells, the pons, the accessory olivary nucleus, and the red nucleus. The similarity of mouse C1qL1 to human C1qL1 suggests a conserved and important role for the protein. In humans, the gene encoding C1qL1 maps to chromosome 17q21.

NCBI and Uniprot Product Information

• NCBI GI #: 5729785
• NCBI GeneID: 10882
• NCBI Accession #: NP_006679.1
• NCBI GenBank Nucleotide #: NM_006688.4
• UniProt Accession #: O75973
• Molecular Weight: 26,453 Da
• NCBI Official Full Name: C1q-related factor
• NCBI Official Synonym Full Names: complement C1q like 1
• NCBI Official Symbol: C1QL1
• NCBI Official Synonym Symbols: CRF; C1QRF; C1QTNF14
• NCBI Protein Information: C1q-related factor
• UniProt Protein Name: C1q-related factor
• Protein Family: C1q-related factor
• UniProt Gene Name: C1QL1
• UniProt Synonym Gene Names: C1QRF; CRF; CTRP14; C1q/TNF-related protein 14

Uniprot Description

May regulate the number of excitatory synapses that are formed on hippocampus neurons. Has no effect on inhibitory synapses ().