Rabbit BTBD1 Polyclonal Antibody | anti-BTBD1 antibody

BTBD1 Rabbit Polyclonal

Cat. Num. AAA767203

• Gene Names: BTBD1; C15orf1; NS5ATP8
• Reactivity: Human, Mouse, Rat
• Applications: ELISA, Western Blot, Immunohistochemistry
• Purity: >=95% as determined by SDS-PAGE; Immunogen Affinity Purified
• Synonyms: BTBD1; Polyclonal Antibody; BTBD1 Rabbit Polyclonal; anti-BTBD1 antibody

• Host: Rabbit
• Reactivity: Human, Mouse, Rat
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: >=95% as determined by SDS-PAGE; Immunogen Affinity Purified
• Form/Format: Liquid
• Sequence Length: 385

• Applicable Applications for anti-BTBD1 antibody: ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
• Immunogen: BTB (POZ) domain containing 1
• Preparation and Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20 degree C for 24 months (Avoid repeated freeze / thaw cycles.)

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded human testis using MBS767203 (BTBD1 antibody) at dilution of 1:100)

Western Blot (WB)

(HeLa cells were subjected to SDS PAGE followed by western blot with MBS767203 (BTBD1 antibody) at dilution of 1:500)

NCBI and Uniprot Product Information

• NCBI GI #: 59814146
• NCBI GeneID: 53339
• NCBI Accession #: NP_001011885.1
• NCBI GenBank Nucleotide #: NM_001011885.1
• Molecular Weight: 42,117 Da
• NCBI Official Full Name: BTB/POZ domain-containing protein 1 isoform 2
• NCBI Official Synonym Full Names: BTB domain containing 1
• NCBI Official Symbol: BTBD1
• NCBI Official Synonym Symbols: C15orf1; NS5ATP8
• NCBI Protein Information: BTB/POZ domain-containing protein 1
• UniProt Protein Name: BTB/POZ domain-containing protein 1
• UniProt Gene Name: BTBD1
• UniProt Synonym Gene Names: C15orf1; NS5ATP8; HCV NS5A-transactivated protein 8
• UniProt Entry Name: BTBD1_HUMAN

NCBI Description

The C-terminus of the protein encoded by this gene binds topoisomerase I. The N-terminus contains a proline-rich region and a BTB/POZ domain (broad-complex, Tramtrack and bric a brac/Pox virus and Zinc finger), both of which are typically involved in protein-protein interactions. Subcellularly, the protein localizes to cytoplasmic bodies. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]

Uniprot Description

BTBD1: Probable substrate-specific adapter of an E3 ubiquitin- protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.

Protein type: Unknown function

Chromosomal Location of Human Ortholog: 15q24

Cellular Component: protein complex

Molecular Function: protein binding

Biological Process: protein ubiquitination; regulation of protein binding