Typical Testing Data/Standard Curve (for reference only)
Rat Glutamate--cysteine ligase catalytic subunit ELISA Kit | Gclc elisa kit
Rat Glutamate--cysteine ligase catalytic subunit ELISA Kit
Typical Testing Data/Standard Curve (for reference only)
Typical Testing Data/Standard Curve (for reference only)
NCBI and Uniprot Product Information
NCBI Description
catalyzes the first step in the synthesis of glutathione [RGD, Feb 2006]
Uniprot Description
GCLC: Defects in GCLC are the cause of hemolytic anemia (HAGGSD). Belongs to the glutamate--cysteine ligase type 3 family.
Protein type: EC 6.3.2.2; Ligase; Other Amino Acids Metabolism - glutathione
Cellular Component: cytosol; glutamate-cysteine ligase complex
Molecular Function: ADP binding; ATP binding; coenzyme binding; glutamate binding; glutamate-cysteine ligase activity; magnesium ion binding; protein heterodimerization activity
Biological Process: aging; apoptotic mitochondrial changes; cell redox homeostasis; cellular response to insulin stimulus; cysteine metabolic process; glutamate metabolic process; glutathione biosynthetic process; glutathione metabolic process; L-ascorbic acid metabolic process; negative regulation of apoptosis; negative regulation of neuron apoptosis; negative regulation of protein ubiquitination; negative regulation of transcription, DNA-dependent; positive regulation of proteasomal ubiquitin-dependent protein catabolic process; regulation of blood vessel size; regulation of mitochondrial depolarization; response to activity; response to arsenic; response to cadmium ion; response to heat; response to hormone stimulus; response to nitrosative stress; response to oxidative stress; response to xenobiotic stimulus
Research Articles on Gclc
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Product Notes
The Rat Gclc gclc (Catalog #AAA2885456) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA2885456 ELISA Kit recognizes Rat Gclc. It is sometimes possible for the material contained within the vial of "Glutamate--cysteine ligase catalytic subunit, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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