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Western Blot (WB) (Western blot analysis of BS69 expression in rat liver (A), rat kidney (B) whole cell lysates.)

Rabbit BS69 Polyclonal Antibody | anti-BS69 antibody

Anti-BS69 Antibody

Gene Names
ZMYND11; BS69; BRAM1; RP11-486H9.1
Reactivity
Human, Mouse, Rat, Monkey
Applications
Western Blot, Immunohistochemistry
Purity
Purified by Immunogen Affinity Chromatography
Synonyms
BS69; Polyclonal Antibody; Anti-BS69 Antibody; BRAM1; Zinc finger MYND domain-containing protein 11; Adenovirus 5 E1A-binding protein; Bone morphogenetic protein receptor-associated molecule 1; Protein BS69; anti-BS69 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Mouse, Rat, Monkey
Clonality
Polyclonal
Specificity
Recognizes endogenous levels of BS69 protein.
Purity/Purification
Purified by Immunogen Affinity Chromatography
Form/Format
Liquid in 0.42% Potassium Phosphate, 0.87% Sodium Chloride, pH 7.3, 30% Glycerol, and 0.01% Sodium Azide.
Applicable Applications for anti-BS69 antibody
Western Blot (WB), Immunohistochemistry (IHC)
Application Notes
WB: 1:500-1:1000
IHC: 1:50-1:200
Immunogen
KLH-conjugated synthetic peptide encompassing a sequence within the center region of human BS69. The exact sequence is proprietary.
Preparation and Storage
Upon delivery aliquot and store at -20 degree C for one year. Avoid freeze/thaw cycles.

Western Blot (WB)

(Western blot analysis of BS69 expression in rat liver (A), rat kidney (B) whole cell lysates.)

Western Blot (WB) (Western blot analysis of BS69 expression in rat liver (A), rat kidney (B) whole cell lysates.)

Immunohistochemistry (IHC)

(Immunohistochemical analysis of BS69 staining in human breast cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX.)

Immunohistochemistry (IHC) (Immunohistochemical analysis of BS69 staining in human breast cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX.)
Related Product Information for anti-BS69 antibody
Rabbit polyclonal antibody to BS69

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
70,963 Da
NCBI Official Full Name
zinc finger MYND domain-containing protein 11 isoform c
NCBI Official Synonym Full Names
zinc finger, MYND-type containing 11
NCBI Official Symbol
ZMYND11
NCBI Official Synonym Symbols
BS69; BRAM1; RP11-486H9.1
NCBI Protein Information
zinc finger MYND domain-containing protein 11; adenovirus 5 E1A-binding protein; bone morphogenetic protein receptor-associated molecule 1
UniProt Protein Name
Zinc finger MYND domain-containing protein 11
UniProt Gene Name
ZMYND11
UniProt Synonym Gene Names
BS69
UniProt Entry Name
ZMY11_HUMAN

NCBI Description

The protein encoded by this gene was first identified by its ability to bind the adenovirus E1A protein. The protein localizes to the nucleus. It functions as a transcriptional repressor, and expression of E1A inhibits this repression. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]

Uniprot Description

ZMYND11: Corepressor of transcription (Probable).

Protein type: Tumor suppressor; Transcription regulation; DNA-binding

Chromosomal Location of Human Ortholog: 10p14

Cellular Component: nucleoplasm; chromosome; nucleus

Molecular Function: protein binding; DNA binding; zinc ion binding; transcription corepressor activity; methylated histone residue binding

Biological Process: negative regulation of JNK cascade; cell proliferation; transcription, DNA-dependent; viral reproduction; negative regulation of transcription from RNA polymerase II promoter; chromatin modification; negative regulation of I-kappaB kinase/NF-kappaB cascade; cell cycle

Disease: Mental Retardation, Autosomal Dominant 30

Research Articles on BS69

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Product Notes

The BS69 zmynd11 (Catalog #AAA8305853) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-BS69 Antibody reacts with Human, Mouse, Rat, Monkey and may cross-react with other species as described in the data sheet. AAA Biotech's BS69 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC). WB: 1:500-1:1000 IHC: 1:50-1:200. Researchers should empirically determine the suitability of the BS69 zmynd11 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "BS69, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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