SDS-Page
(Detection of BRIX with MBS621053. Cell lysates were resolved by SDS-PAGE, transferred to an Immobilon-P membrane and immunoblotted with 1ug/ml MBS621053.)
Goat anti-Human Brix Domain Containing 2 Polyclonal Antibody | anti-BRIX1 antibody
Brix Domain Containing 2 (BXDC2, FLJ11100, Ribosome biogenesis protein Brix, BRIX)
Gene Names
BRIX1; BRIX; BXDC2; FLJ11100
Reactivity
Human
Applications
ELISA, Western Blot
Purity
Affinity PurifiedPurified by immunoaffinity chromatography.
Synonyms
Brix Domain Containing 2; Polyclonal Antibody; Brix Domain Containing 2 (BXDC2; FLJ11100; Ribosome biogenesis protein Brix; BRIX); Anti -Brix Domain Containing 2 (BXDC2; anti-BRIX1 antibody
Host
Goat
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Specificity
Recognizes human BRIX. Species sequence homology: mouse (93%).
Purity/Purification
Affinity Purified
Purified by immunoaffinity chromatography.
Purified by immunoaffinity chromatography.
Form/Format
Supplied as a lyophilized powder from 0.2um filtered solution in PBS, 5% trehalose. Reconstitute with sterile PBS, sterile 40-50% glycerol.
Applicable Applications for anti-BRIX1 antibody
ELISA (EL/EIA), Western Blot (WB)
Application Notes
Suitable for use in ELISA and Western Blot.
Dilution: Western Blot: 1ug/ml
ELISA: 0.5-1ug/ml
Dilution: Western Blot: 1ug/ml
ELISA: 0.5-1ug/ml
Immunogen
E. coli-derived, recombinant human BRIX (aa131-353).
Preparation and Storage
Lyophilized powder may be stored at -20 degree C. Stable for 12 months at -20 degree C. Reconstitute with sterile PBS, sterile 40-50% glycerol, aliquot and store at -20 degree C. Reconstituted product is stable for 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
SDS-Page
(Detection of BRIX with MBS621053. Cell lysates were resolved by SDS-PAGE, transferred to an Immobilon-P membrane and immunoblotted with 1ug/ml MBS621053.)
SDS-Page
(Detection of BRIX with MBS621053. Cell lysates were resolved by SDS-PAGE, transferred to an Immobilon-P membrane and immunoblotted with 1ug/ml MBS621053.)
Related Product Information for anti-BRIX1 antibody
BRIX (Biogenesis of ribosomes in Xenopus; also BRIX domain-containing protein 2) is a 41kD (predicted) member of the BXDC2 family of proteins. It is found in nucleoli, and appears to participate in the formation of a complex associated with pre-rRNA and enzymes that generate 60S ribosomal subunits. Human BRIX is 353 amino acids in length. It is characterized by the presence of a BRIX domain that lies between aa 60-249. There is one splice variant that shows a 17aa substitution for aa11-27. Over aa131-353, human BRIX shares 93% aa identity with mouse BRIX.
Product Categories/Family for anti-BRIX1 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
41,401 Da
NCBI Official Full Name
Brix domain containing 2
NCBI Official Synonym Full Names
BRX1, biogenesis of ribosomes, homolog (S. cerevisiae)
NCBI Official Symbol
BRIX1
NCBI Official Synonym Symbols
BRIX; BXDC2; FLJ11100
NCBI Protein Information
ribosome biogenesis protein BRX1 homolog; OTTHUMP00000221047; brix domain containing 2; brix domain-containing protein 2
UniProt Protein Name
Ribosome biogenesis protein BRX1 homolog
UniProt Gene Name
BRIX1
UniProt Synonym Gene Names
BRIX; BXDC2
UniProt Entry Name
BRX1_HUMAN
Uniprot Description
BXDC2: Required for biogenesis of the 60S ribosomal subunit. Belongs to the BRX1 family.
Protein type: RNA-binding; Ligase; Nucleolus
Chromosomal Location of Human Ortholog: 5p13.2
Cellular Component: nucleolus; nucleus
Biological Process: ribosomal large subunit assembly and maintenance
Similar Products
Product Notes
The BRIX1 brix1 (Catalog #AAA621053) is an Antibody produced from Goat and is intended for research purposes only. The product is available for immediate purchase. The Brix Domain Containing 2 (BXDC2, FLJ11100, Ribosome biogenesis protein Brix, BRIX) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's Brix Domain Containing 2 can be used in a range of immunoassay formats including, but not limited to, ELISA (EL/EIA), Western Blot (WB). Suitable for use in ELISA and Western Blot. Dilution: Western Blot: 1ug/ml ELISA: 0.5-1ug/ml. Researchers should empirically determine the suitability of the BRIX1 brix1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Brix Domain Containing 2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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