Rabbit anti-Human BRD1 Polyclonal Antibody | anti-BRD1 antibody

BRD1 Antibody

Cat. Num. AAA9629351

• Gene Names: BRD1; BRL; BRPF1; BRPF2
• Reactivity: Human
• Applications: ELISA
• Purity: The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin (Thermo Fisher Scientific).
• Synonyms: BRD1; Polyclonal Antibody; BRD1 Antibody; BR140-like protein; BRD1_HUMAN; BRL; Bromodomain and PHD finger-containing protein 2; Bromodomain containing 1; Bromodomain-containing protein 1; BRPF1; BRPF2; DKFZp686F0325; anti-BRD1 antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Isotype: Rabbit IgG
• Specificity: BRD1 Antibody detects endogenous levels of total BRD1.
• Purity/Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin (Thermo Fisher Scientific).
• Form/Format: Liquid. Rabbit IgG in phosphate buffered saline, pH7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
• Concentration: 1mg/ml (varies by lot)

• Applicable Applications for anti-BRD1 antibody: ELISA (EIA)(peptide)
• Application Notes: ELISA(peptide): 1:20000-1:40000
• Immunogen: A synthesized peptide derived from Human MYOCD.
• Conjugation: Unconjugated
• Subunit Structure: Component of the MOZ/MORF complex composed at least of ING5, KAT6A, KAT6B, MEAF6 and one of BRPF1, BRD1/BRPF2 and BRPF3. Interacts (via PHD-type zinc finger domain) with unmodified histone H3. Interacts (via PWWP domain) with dimethylated and trimethylated 'Lys-79' on histone H3.
• Tissue Specificity: Highly expressed in testis.
• Function: Component of the MOZ/MORF complex which has a histone H3 acetyltransferase activity.
• Preparation and Storage: Store at -20 degree C. Stable for 12 months from date of receipt.

Product Categories/Family for anti-BRD1 antibody

Nucleus; Primary

NCBI and Uniprot Product Information

• NCBI GI #: 756141031
• NCBI GeneID: 23774
• NCBI Accession #: NP_001291737.1
• NCBI GenBank Nucleotide #: NM_001304808.1
• UniProt Accession #: O95696; A6ZJA4
• Molecular Weight: 133,243 Da
• NCBI Official Full Name: bromodomain-containing protein 1 isoform 1
• NCBI Official Synonym Full Names: bromodomain containing 1
• NCBI Official Symbol: BRD1
• NCBI Official Synonym Symbols: BRL; BRPF1; BRPF2
• NCBI Protein Information: bromodomain-containing protein 1
• UniProt Protein Name: Bromodomain-containing protein 1
• UniProt Gene Name: BRD1
• UniProt Synonym Gene Names: BRL; BRPF2
• UniProt Entry Name: BRD1_HUMAN

Uniprot Description

BRD1: a nuclear protein containing a bromo-domain, a PHD domain, and a PWWP domain. Encoded by a susceptibility gene for schizophrenia and bipolar affective disorder. May play a role in neurodevelopment.

Protein type: Cell development/differentiation

Chromosomal Location of Human Ortholog: 22q13.33

Cellular Component: nucleoplasm; nucleus

Molecular Function: histone binding