Western Blot (WB)
(BNIP2 Antibody (C-term) western blot analysis in A549 cell line lysates (35ug/lane).This demonstrates the BNIP2 antibody detected the BNIP2 protein (arrow).)
Rabbit anti-Human BNIP2 Polyclonal Antibody | anti-BNIP2 antibody
BNIP2 Antibody (C-term)
Western Blot (WB)
(BNIP2 Antibody (C-term) western blot analysis in A549 cell line lysates (35ug/lane).This demonstrates the BNIP2 antibody detected the BNIP2 protein (arrow).)
Western Blot (WB)
(BNIP2 Antibody (C-term) western blot analysis in A549 cell line lysates (35ug/lane).This demonstrates the BNIP2 antibody detected the BNIP2 protein (arrow).)
Immunohistochemistry (IHC)
(BNIP2 Antibody (C-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human placenta tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of BNIP2 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.)
Immunohistochemistry (IHC)
(BNIP2 Antibody (C-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human placenta tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of BNIP2 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.)
kd-interacting protein (BNIP) family. Though the specific function
is unknown, it interacts with the E1B 19 kDa protein which is
responsible for the protection of virally-induced cell death, as
well as E1B 19 kDa-like sequences of BCL2, also an apoptotic
protector.
Shimada, M., et al. Hum. Genet. 128(4):433-441(2010)
Valencia, C.A., et al. Biochem. Biophys. Res. Commun. 364(3):495-501(2007)
Zhou, Y.T., et al. Exp. Cell Res. 303(2):263-274(2005)
Shang, X., et al. J. Biol. Chem. 278(46):45903-45914(2003)
NCBI and Uniprot Product Information
NCBI Description
This gene is a member of the BCL2/adenovirus E1B 19 kd-interacting protein (BNIP) family. It interacts with the E1B 19 kDa protein, which protects cells from virally-induced cell death. The encoded protein also interacts with E1B 19 kDa-like sequences of BCL2, another apoptotic protector. [provided by RefSeq, Mar 2011]
Uniprot Description
BNIP2: Implicated in the suppression of cell death. Interacts with the BCL-2 and adenovirus E1B 19 kDa proteins. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Apoptosis; Motility/polarity/chemotaxis
Chromosomal Location of Human Ortholog: 15q22.2
Cellular Component: intracellular membrane-bound organelle; perinuclear region of cytoplasm; cytoplasm; nuclear envelope; cytosol
Molecular Function: identical protein binding; protein binding; calcium ion binding; GTPase activator activity
Biological Process: muscle cell differentiation; apoptosis; positive regulation of muscle cell differentiation; negative regulation of apoptosis; positive regulation of GTPase activity
Research Articles on BNIP2
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Product Notes
The BNIP2 bnip2 (Catalog #AAA9206628) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 285-316. The BNIP2 Antibody (C-term) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's BNIP2 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA), Immunohistochemistry (IHC). WB~~1:1000. Researchers should empirically determine the suitability of the BNIP2 bnip2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "BNIP2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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