Western Blot (WB)
(Mouse Bmpr1a Antibody (Center) western blot analysis in SK-BR-3 cell line lysates (35ug/lane).This demonstrates the Bmpr1a antibody detected the Bmpr1a protein (arrow).)
Rabbit Bmpr1a Polyclonal Antibody | anti-Bmpr1a antibody
Mouse Bmpr1a Antibody (Center)
Western Blot (WB)
(Mouse Bmpr1a Antibody (Center) western blot analysis in SK-BR-3 cell line lysates (35ug/lane).This demonstrates the Bmpr1a antibody detected the Bmpr1a protein (arrow).)
Western Blot (WB)
(Mouse Bmpr1a Antibody (Center) western blot analysis in SK-BR-3 cell line lysates (35ug/lane).This demonstrates the Bmpr1a antibody detected the Bmpr1a protein (arrow).)
Leung, A.W., et al. Dev. Dyn. 239(9):2319-2329(2010)
Mira, H., et al. Cell Stem Cell 7(1):78-89(2010)
Libusova, L., et al. Development 137(14):2297-2305(2010)
Caronia, G., et al. J. Neurosci. 30(18):6291-6301(2010)
NCBI and Uniprot Product Information
Uniprot Description
BMPR1A: a serine/threonine-protein kinase receptor for Bone morphogenetic protein-2 and -4 (BMP-2 and BMP-4). Defects in BMPR1A are a cause of juvenile polyposis syndrome (JPS) and Cowden disease (CD), a cancer syndrome characterized by multiple hamartomas and by a high risk for breast, thyroid and endometriel cancers.
Protein type: Membrane protein, integral; EC 2.7.11.30; Protein kinase, Ser/Thr (receptor); Protein kinase, TKL; Kinase, protein; TKL group; STKR family; Type1 subfamily
Cellular Component: membrane; cell soma; dendrite; integral to membrane; plasma membrane; caveola
Molecular Function: transferase activity; protein serine/threonine kinase activity; protein homodimerization activity; metal ion binding; transferase activity, transferring phosphorus-containing groups; nucleotide binding; kinase activity; SMAD binding; ATP binding; transmembrane receptor protein serine/threonine kinase activity; protein kinase activity; receptor signaling protein serine/threonine kinase activity
Biological Process: transcription from RNA polymerase II promoter; neural plate mediolateral pattern formation; heart morphogenesis; paraxial mesoderm development; developmental growth; hindlimb morphogenesis; neural crest cell development; positive regulation of transcription, DNA-dependent; heart development; mesendoderm development; paraxial mesoderm structural organization; dorsal/ventral axis specification; palate development; protein amino acid phosphorylation; negative regulation of neurogenesis; anterior/posterior pattern formation; BMP signaling pathway; transmembrane receptor protein serine/threonine kinase signaling pathway; positive regulation of mesenchymal cell proliferation; ectoderm development; embryonic morphogenesis; cell differentiation; Mullerian duct regression; nervous system development; regulation of endothelial cell proliferation; somitogenesis; in utero embryonic development; stem cell maintenance; lateral mesoderm development; positive regulation of bone mineralization; pattern specification process; regulation of endothelial cell differentiation; odontogenesis of dentine-containing teeth; positive regulation of osteoblast differentiation; mesoderm formation; dorsal/ventral pattern formation; pituitary gland development; cartilage development; embryonic organ development; immune response; embryonic digit morphogenesis; phosphorylation; regulation of lateral mesodermal cell fate specification; positive regulation of epithelial cell proliferation; lung development; endoderm development
Research Articles on Bmpr1a
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Product Notes
The Bmpr1a bmpr1a (Catalog #AAA9205330) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 170-197. The Mouse Bmpr1a Antibody (Center) reacts with Human, mouse (Predicted Reactivity: Rat) and may cross-react with other species as described in the data sheet. AAA Biotech's Bmpr1a can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). WB~~1:1000. Researchers should empirically determine the suitability of the Bmpr1a bmpr1a for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Bmpr1a, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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