Western Blot (WB)
(Western blot of BLIMP1 / PRDM1 antibody. Nuclear extract of Saos-2 cells (20 ug per lane) probed with BLIMP1 / PRDM1 antibody (pAb) at a dilution of 1:1,000.)
Rabbit anti-Human BLIMP1/PRDM1 Polyclonal Antibody | anti-BLIMP1/PRDM1 antibody
BLIMP1/PRDM1 antibody (pAb)
Gene Names
PRDM1; BLIMP1; PRDI-BF1
Reactivity
Human
Applications
Immunofluorescence, Western Blot
Purity
Affinity Purified
Synonyms
BLIMP1/PRDM1; Polyclonal Antibody; BLIMP1/PRDM1 antibody (pAb); PRDI-BF1; anti-BLIMP1/PRDM1 antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Affinity Purified
Form/Format
Purified IgG in 70mM Tris (pH8), 105mM NaCl, 31mM glycine, 0.07mM EDTA, 30% glycerol and 0.035% sodium azide. Sodium azide is highly toxic.
Applicable Applications for anti-BLIMP1/PRDM1 antibody
Immunofluorescence (IF), Western Blot (WB)
Application Notes
Applications Validated:
WB: 1:500-1:1,000 dilution
WB: 1:500-1:1,000 dilution
Immunogen
This BLIMP1/PRDM1 antibody was raised against a peptide within the N-terminal half of human BLIMP1/PRDM1.
Preparation and Storage
Some products may be shipped at room temperature. This will not affect their stability or performance. Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20 degree C for up to 2 years. Keep all reagents on ice when not in storage.1ug/ul
Western Blot (WB)
(Western blot of BLIMP1 / PRDM1 antibody. Nuclear extract of Saos-2 cells (20 ug per lane) probed with BLIMP1 / PRDM1 antibody (pAb) at a dilution of 1:1,000.)
Western Blot (WB)
(Western blot of BLIMP1 / PRDM1 antibody. Nuclear extract of Saos-2 cells (20 ug per lane) probed with BLIMP1 / PRDM1 antibody (pAb) at a dilution of 1:1,000.)
Related Product Information for anti-BLIMP1/PRDM1 antibody
Short Description: Our BLIMP1/PRDM1 antibody (pAb) was raised in a Rabbit host. It has been validated for use in Immunofluorescence and Western blot; it has been shown to react with Human samples.
Background: BLIMP1/PRDM1 (Beta-interferon gene positive regulatory domain I-binding factor, PR domain-containing protein 1 Positive regulatory domain I-binding factor 1) is a DNA sequence-specific transcriptional repressor that binds specifically to the PRDI element in the promoter of the beta-interferon gene, as well as other genes. It is required for maturation of B-lymphocytes into immunoglobin secreting plasma cells through direct repression of transcription factors such as Pax5, Bcl6, and Myc, which function in the lineage commitment and proliferation of B cells. BLIMP1/PRDM1 contains an N-terminal SET domain and four C-terminal C2H2-type zinc-finger motifs. It is also required for effector T-cell function and for the specification of primordial germ cell lineages.
Background: BLIMP1/PRDM1 (Beta-interferon gene positive regulatory domain I-binding factor, PR domain-containing protein 1 Positive regulatory domain I-binding factor 1) is a DNA sequence-specific transcriptional repressor that binds specifically to the PRDI element in the promoter of the beta-interferon gene, as well as other genes. It is required for maturation of B-lymphocytes into immunoglobin secreting plasma cells through direct repression of transcription factors such as Pax5, Bcl6, and Myc, which function in the lineage commitment and proliferation of B cells. BLIMP1/PRDM1 contains an N-terminal SET domain and four C-terminal C2H2-type zinc-finger motifs. It is also required for effector T-cell function and for the specification of primordial germ cell lineages.
Product Categories/Family for anti-BLIMP1/PRDM1 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
76,835 Da
NCBI Official Full Name
PR domain zinc finger protein 1 isoform 1
NCBI Official Synonym Full Names
PR domain containing 1, with ZNF domain
NCBI Official Symbol
PRDM1
NCBI Official Synonym Symbols
BLIMP1; PRDI-BF1
NCBI Protein Information
PR domain zinc finger protein 1; BLIMP-1; PRDI-binding factor-1; B-lymphocyte-induced maturation protein 1; beta-interferon gene positive-regulatory domain I binding factor
UniProt Protein Name
PR domain zinc finger protein 1
UniProt Gene Name
PRDM1
UniProt Synonym Gene Names
BLIMP1; PRDI-BF1
UniProt Entry Name
PRDM1_HUMAN
NCBI Description
This gene encodes a protein that acts as a repressor of beta-interferon gene expression. The protein binds specifically to the PRDI (positive regulatory domain I element) of the beta-IFN gene promoter. Transcription of this gene increases upon virus induction. Two alternatively spliced transcript variants that encode different isoforms have been reported. [provided by RefSeq, Jul 2008]
Research Articles on BLIMP1/PRDM1
Similar Products
Product Notes
The BLIMP1/PRDM1 prdm1 (Catalog #AAA388737) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The BLIMP1/PRDM1 antibody (pAb) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's BLIMP1/PRDM1 can be used in a range of immunoassay formats including, but not limited to, Immunofluorescence (IF), Western Blot (WB). Applications Validated: WB: 1:500-1:1,000 dilution. Researchers should empirically determine the suitability of the BLIMP1/PRDM1 prdm1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "BLIMP1/PRDM1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.
