Rabbit BEX3 Polyclonal Antibody | anti-BEX3 antibody
BEX3 Antibody
Gene Names
NGFRAP1; Bex; BEX3; NADE; HGR74; DXS6984E
Reactivity
Human, Mouse, Rat
Applications
ELISA
Purity
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin (Thermo Fisher Scientific).
Synonyms
BEX3; Polyclonal Antibody; BEX3 Antibody; Bex; BEX3_HUMAN; Brain expressed X linked 3 (mouse) homolog; brain expressed; X-linked 3; Brain-expressed X-linked gene 3; Brain-expressed X-linked protein 3; DXS6984E; HGR74; NADE; Nerve growth factor receptor (TNFRSF16) associated protein 1; Nerve growth factor receptor associated protein 1; Nerve growth factor receptor-associated protein 1; NGFR-associated protein 1; NGFRAP1; Ovarian granulosa cell 13.0 kDa protein HGR74; ovarian granulosa cell protein (13kD); Ovarian granulosa cell protein; p75NTR associated cell death executor; p75NTR-associated cell death executor; Protein BEX3; anti-BEX3 antibody
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
Rabbit IgG
Specificity
BEX3 Antibody detects endogenous levels of BEX3.
Purity/Purification
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin (Thermo Fisher Scientific).
Form/Format
Liquid. Rabbit IgG in phosphate buffered saline, pH7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration
1mg/ml (varies by lot)
Applicable Applications for anti-BEX3 antibody
ELISA (EIA)(peptide)
Application Notes
ELISA(peptide): 1:20000-1:40000
Immunogen
A synthesized peptide derived from human BEX3.
Conjugation
Unconjugated
Similarity
The nuclear export signal is required for export from the nucleus and the interactions with itself and p75NTR/NGFR. Belongs to the BEX family.
Post Translational Modifications
Ubiquitinated. Degraded by the proteasome (By similarity).
Subunit Structure
Self-associates. Binds to the DEATH domain of p75NTR/NGFR. Interacts with 14-3-3 epsilon (YWHAE). Interacts with DIABLO/SMAC.
Tissue Specificity
Found in ovarian granulosa cells, testis, prostate and seminal vesicle tissue. High levels also detected in liver.
Function
May be a signaling adapter molecule involved in p75NTR-mediated apoptosis induced by NGF. Plays a role in zinc-triggered neuronal death (By similarity). May play an important role in the pathogenesis of neurogenetic diseases.
Note
huttles between the cytoplasm and the nucleus. Associates with replicating mitochondria (By similarity).
Preparation and Storage
Store at -20 degree C. Stable for 12 months from date of receipt.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
111
NCBI Official Full Name
Protein BEX3
NCBI Official Synonym Full Names
nerve growth factor receptor (TNFRSF16) associated protein 1
NCBI Official Symbol
NGFRAP1
NCBI Official Synonym Symbols
Bex; BEX3; NADE; HGR74; DXS6984E
NCBI Protein Information
protein BEX3; brain-expressed X-linked protein 3; p75NTR-associated cell death executor; ovarian granulosa cell 13.0 kDa protein HGR74
UniProt Protein Name
Protein BEX3
Protein Family
UniProt Gene Name
NGFRAP1
UniProt Synonym Gene Names
BEX3; DXS6984E; NADE
UniProt Entry Name
BEX3_HUMAN
Similar Products
Product Notes
The BEX3 ngfrap1 (Catalog #AAA9629787) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The BEX3 Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's BEX3 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA)(peptide). ELISA(peptide): 1:20000-1:40000. Researchers should empirically determine the suitability of the BEX3 ngfrap1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "BEX3, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.
