Rabbit anti-Human BEST4 Polyclonal Antibody | anti-BEST4 antibody
Bestrophin 4 Antibody Affinity Purified
ELISA: 1:2,000
Immunoprecipitation: 1:200
Western Blot: 1:500-1:1,000
Forms calcium-sensitive chloride channels. Permeable to bicarbonate.
NCBI and Uniprot Product Information
NCBI Description
This gene is a member of the bestrophin gene family of anion channels. Bestrophin genes share a similar gene structure with highly conserved exon-intron boundaries, but with distinct 3' ends. Bestrophins are transmembrane proteins that contain a homologous region rich in aromatic residues, including an invariant arg-phe-pro motif. Mutation in one of the family members (bestrophin 1) is associated with vitelliform macular dystrophy. The bestrophin 4 gene is predominantly expressed in the colon. [provided by RefSeq, Jul 2008]
Uniprot Description
BEST4: Forms calcium-sensitive chloride channels. Permeable to bicarbonate. Belongs to the bestrophin family.
Protein type: Membrane protein, multi-pass; Transporter; Transporter, ion channel; Membrane protein, integral
Chromosomal Location of Human Ortholog: 1p34.1
Cellular Component: integral to plasma membrane
Molecular Function: chloride channel activity
Research Articles on BEST4
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Product Notes
The BEST4 best4 (Catalog #AAA540590) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Bestrophin 4 Antibody Affinity Purified reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's BEST4 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), IMM, Western Blot (WB). Dot Blot: 1:2,000 ELISA: 1:2,000 Immunoprecipitation: 1:200 Western Blot: 1:500-1:1,000. Researchers should empirically determine the suitability of the BEST4 best4 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "BEST4, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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